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Functional resting state connectivity is differentially associated with IL-6 and TNF-α in depression and in healthy controls.
Sci Rep
January 2025
Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, J5, 68159, Mannheim, Germany.
Inflammatory processes have been implicated in the pathophysiology of depression. In human studies, inflammation has been shown to act as a critical disease modifier, promoting susceptibility to depression and modulating specific endophenotypes of depression. However, there is scant documentation of how inflammatory processes are associated with neural activity in patients with depression.
View Article and Find Full Text PDFBrain health in Norwegian female former top-level football players: a protocol for a longitudinal cohort study.
BMJ Open
January 2025
Oslo Sports Trauma Research Centre, Department of Sport Sciences, Norwegian School of Sports Sciences, Oslo, Oslo, Norway.
Introduction: Repetitive head impacts (RHI) in sports may represent a risk factor for long-term cognitive and neurological sequelae. Recent studies have identified an association between playing football at the top level and an elevated risk of cognitive impairment and neurodegenerative disease. However, these were conducted on men, and there is a knowledge gap regarding these risks in female athletes.
View Article and Find Full Text PDFCharacteristics of upper lumbar spondylolysis in children.
Spine J
January 2025
Department of Orthopaedic Surgery, Anshin Hospital, Kobe, Japan.
Background: Pediatric lumbar spondylolysis (LS) is common in junior and senior high school athletes. Lower LS (L4-L5 level) is more common in children, and upper LS (L1-L3 level) is relatively rare; therefore, the pathogenesis of upper LS remains unclear.
Purpose: To elucidate the mechanisms of upper LS by identifying and comparing characteristics between upper and lower LS cases.
What is the clinical importance of radiographic changes around the humeral component in anatomic shoulder arthroplasty? A minimum 4-year follow-up study.
J Shoulder Elbow Surg
January 2025
Investigation Performed at the University of Washington, Department of Orthopaedic Surgery and Sports Medicine, Seattle, WA, USA. Electronic address:
Background: While stress shielding and adaptive bone changes around the humeral component are often observed after shoulder arthroplasty, the potential causative factors and clinical significance of these findings at mid-term follow-up have not been well elucidated. The purpose of this study was to investigate the frequency, patterns and clinical significance of radiographic findings around the humeral component of total shoulder arthroplasty (TSA) and hemiarthroplasty (HA) at minimum 4-year follow-up.
Methods: The 6-week and minimum 4-year radiographs of patients who underwent HA and TSA were evaluated for filling ratios, changes in the humeral bone surrounding the component, and component shift or subsidence.
Cervical extensor muscle activity during neck tasks in individuals with and without neck pain: A systematic review.
Ann Phys Rehabil Med
January 2025
Department of Physical Activity and Rehabilitation Sciences, University of Liège, Allée des Sports, 2, 4000 Liège, Belgium.
Background: In the context of neck pain, neck muscle activity adapts through diverse regional coordination modifications during tasks. Although patterns of cervical flexor muscle impairment are well-documented, patterns in the cervical extensor muscles are less clear, hindering assessment and treatment. Despite studies revealing adaptations in the cervical extensor muscles, outcome measure heterogeneity complicates interpretation, particularly between superficial and deep muscles.
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