Objective: This study was carried out to show possible similarities between discoid lupus erythematosus clinical signs and histopathological findings and dermatophytosis.
Patient And Methods: A 43-year-old woman with diffused erythematous scaling lesions on her neck was studied. Skin biopsy was performed using H&E and PAS staining. Direct microscopic examination and mycological culture of specimens were done as well.
Results: Histopathological examination suggested she was suffering from discoid lupus erythematosus; however mycological findings confirmed Trichophyton verrucosum as the etiologic agent of lesions. She was successfully treated with oral terbinafine and clotrimazole cream.
Conclusion: Regarding to the results of this study, there are some similarities between dermatophytosis and skin infections such as discoid lupus erythematosus.
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http://dx.doi.org/10.1016/j.mycmed.2011.12.001 | DOI Listing |
Introduction: Previous studies have investigated the density of dermal papillae (DP) in normal skin using reflectance confocal microscopy (RCM), a non-invasive imaging technique that allows a real time, high-resolution imaging of the skin, although no histological confirmation was provided. The aim of the present study was to compare the RCM evaluation of DP density in healthy skin with horizontal histopathological sections (HHS), a technique that provides a horizontal view of the skin.
Methods: Ten adult patients were selected, and a healthy skin area was marked for RCM examination and a subsequent 5-mm punch biopsy that was processed for HHS.
An Bras Dermatol
January 2025
Department of Pathology, Faculty of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Int J Dermatol
January 2025
Department of Dermatology, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.
SAGE Open Med Case Rep
January 2025
Division of Dermatology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Discoid lupus erythematosus is a chronic, recurring, autoimmune skin disease causing annular, scarring plaques on the head and neck. Deucravacitinib, a tyrosine kinase 2 inhibitor in the Janus kinase inhibitor family, represents an emerging treatment option in systemic lupus erythematosus with potential applicability to discoid lupus erythematosus. We describe a 48-year-old woman with multiple treatment-refractory scalp plaques and associated alopecia treated with deucravacitinib.
View Article and Find Full Text PDFVet Clin North Am Small Anim Pract
January 2025
Pathobiology University of Pennsylvania, School of Veterinary Medicine, 3900 Delancey Street, MJR VHUP, Room 4040, Philadelphia, PA 19104, USA.
Nasal planum dermatoses in dogs can be infectious, immune-mediated, allergic, neoplastic, and metabolic in nature. Recognizing key lesions and features and knowing how and when to biopsy can help distinguish between similar diseases. The focus of this article is to review the most commonly encountered nasal planum dermatoses in dogs and to enable the veterinary practitioner to recognize and differentiate between them to obtain a diagnosis.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!