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Plasma transfusion and hospital mortality in moderate-severe traumatic brain injury.
Injury
December 2024
Division of Acute Care Surgery, Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA; Critical Illness, Brain Dysfunction, And Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA; Surgical Service, Nashville VA Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA.
Background: Prior research suggests that plasma may improve outcomes in traumatic brain injury (TBI). We examined the association between plasma administration and mortality in moderate-severe TBI in a large retrospective cohort, hypothesizing plasma is associated with decreased mortality after accounting for confounding covariates.
Materials And Methods: Patients from the 2017-2020 Trauma Quality Improvement Program (TQIP) dataset ≥18 years with moderate-severe TBI were included.
Hepatic artery pseudoaneurysm-the Mayo Clinic experience and literature review.
Front Med (Lausanne)
December 2024
Department of Hospital Internal Medicine, Mayo Clinic, Jacksonville, FL, United States.
Introduction: Hepatic artery pseudoaneurysm (HAP) is a rare and potentially life-threatening condition associated with high mortality. This study aims to review the etiology, clinical manifestations, management, and outcomes of patients diagnosed and treated for HAP at the Mayo Clinic.
Methodology: This study was a retrospective chart review of medical records for patients diagnosed and treated for hepatic artery pseudoaneurysm (HAP) at the Mayo Clinic (Florida, Minnesota, and Arizona) between September 1, 1998, and June 30, 2022.
Correlation and mediation analysis between plasmapheresis donation behavior and bone mineral density and bone metabolism biomarkers: a cross-sectional study based on plasmapheresis donors at high risk of osteoporosis in China.
PeerJ
December 2024
Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu, China.
Background: As a group of more than 3.67 million people, the bone health of Chinese plasmapheresis donors, which the main population is also a risk group of osteoporosis (OP), has raised concerns. Therefore, this article investigates the relationship between bone mineral density (BMD), bone metabolism indicators, and plasmapheresis donation behavior among some high-risk plasmapheresis donors for OP in China, and further explores the mediating factors through reasonable statistical methods.
View Article and Find Full Text PDFImpact of antithrombotic medication on post operative outcome of low-power HoLEP.
Fr J Urol
December 2024
Urology department, CH Périgueux, France. Electronic address:
Purpose: To study the impact of antithrombotic medication on the postoperative outcome of patients undergoing low-power holmium laser enucleation of the prostate (LP-HoLEP) Method: Data about 432 patients operated between 2017 and 2023 in 2 centers were retrospectively analyzed. Patients were categorized based on their antithrombotic therapy into 3 groups: a control group with no antithrombotic treatment, an anticoagulated (AC) group and a group receiving platelet aggregation inhibitors (PAI). The primary objective was to compare the average duration of postoperative bladder irrigation between the three groups.
View Article and Find Full Text PDFVaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but serious prothrombotic adverse event following vaccination with adenovector-based COVID-19 vaccines. Laboratory findings indicate that anti-platelet factor 4 (PF4) immunoglobulin G antibodies are the causing factor for the onset of thromboembolic events in VITT. However, molecular mechanisms of cellular interactions, signaling pathways and involvement of different cell types in VITT antibody-mediated thrombosis are not fully understood.
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