AI Article Synopsis
- Research shows that spray drying can enhance vaccine stability and create new delivery methods, showing promising potential.
- Despite its advantages, the pharmaceutical industry has not yet adopted spray drying for vaccine manufacturing.
- The article reviews current spray-drying technology and explores the challenges and opportunities for its future use in vaccines.
Article Abstract
Research on spray drying as a processing method to improve vaccine stabilization and to enable novel routes of vaccine delivery has produced promising results; however, the method has yet to be adopted for the manufacture of vaccine products by the pharmaceutical industry. This article reviews the status of spray-drying technology and discusses barriers and opportunities for its future application to vaccines.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1586/erv.12.101 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Updates on the conversion of nanosuspensions to solid oral dosage forms.
J Food Drug Anal
December 2024
Department of Pharmacy, School of Health Sciences, Frederick University, Nicosia, 1036, Cyprus.
Pharmaceutical nanosuspensions, also called nanocrystals, are heterogeneous mainly aqueous dispersions of insoluble drug particles stabilised by surfactants and/or polymers. Nanosuspensions as liquid formulations suffer from instability. Solidification of nanosuspensions to solid dosage forms is a way to combine the advantages of nanocrystals with the advantages of the solid state.
View Article and Find Full Text PDFAssessing quality and polyphenol in vitro bioaccessibility in healthy jelly gummies with microencapsulated and non-encapsulated pomegranate peel extract.
Food Chem
December 2024
Departamento de Nutrición y Dietética, Escuela de Ciencias de la Salud, Facultad de Medicina, Pontificia Universidad Católica de Chile, 7820436 Santiago, Chile.. Electronic address:
Background: Pomegranate peel extract (PPE) is rich in polyphenols, notably punicalagin and ellagic acid, but is sensitive to environmental degradation and has low bioavailability. Microencapsulation can enhance PPE stability and bioaccessibility, making it suitable for functional foods like jelly gummies (JG). JG containing microencapsulated PPE (MPPE) have not been studied.
View Article and Find Full Text PDFEvaluation of the antimicrobial effect of encapsulated cumin seed essential oil in chickpea protein-maltodextrin matrix and its potential to extend the shelf life of meatballs.
Food Sci Technol Int
January 2025
Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Maslak, Istanbul, Türkiye.
This study aimed to evaluate the antimicrobial effectiveness of cumin seed essential oil (CEO) after encapsulation in chickpea protein-maltodextrin matrix by spray drying and to provide insight into potential use as a natural ingredient in meat-based products. The surface morphology results of encapsulated CEO showed the dispersion in the wall material matrix, and the observed specific common peaks in the FT-IR spectra of encapsulated and non-encapsulated CEO proved the successful encapsulation. The antibacterial activity of non-encapsulated CEO against BC1402, ATCC 27853, Typhimurium ATCC 0402, ATCC 25923 were first evaluated by disc diffusion assay.
View Article and Find Full Text PDFZein-based nanoparticulate systems: a journey through fabrication, targeting strategies and biomedical applications.
J Biomater Sci Polym Ed
January 2025
Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER)-Ahmedabad, Gandhinagar, India.
Zein, a plant-based protein obtained from the endosperm of corn ( L.) received colossal attention in recent years due to its promising features like being economical, mucoadhesive, gastro-resistant, biocompatible and aids to load hydrophilic and hydrophobic therapeutic agents. It can be employed for the fabrication of various drug delivery systems such as nanoparticles, micelles, hydrogels, nanofibers and films.
View Article and Find Full Text PDFAmorphous-dominated MgO hollow spheres enhanced fluoride adsorption: Mechanism analysis and machine learning prediction.
J Chem Phys
January 2025
School of Mechanical Engineering, Liaoning Petrochemical University, Fushun 113001, Liaoning, China.
Amorphous-dominated magnesium oxide hollow spheres (A-MgO) were prepared using a spray-drying method in this study. These hollow spheres exhibited excellent sphericity, large specific surface areas, and abundant porosity. A-MgO exhibited outstanding fluoride adsorption properties, with a maximum adsorption capacity of 260.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!