The ability of the retinoid compounds, all-trans and 13-cis, to inhibit the growth of bladder tumour cells was investigated in primary tissue culture. A significant decrease in tumour growth was evident in 9 human bladder cancer patients. Since retinoid compounds are able to delay the progression or induction of tumours in primary tissue culture, their trial use as intravesical agents may be warranted.
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| http://dx.doi.org/10.1111/j.1464-410x.1990.tb14696.x | DOI Listing |
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