AI Article Synopsis
- A group of neutral thiourea receptors can facilitate the exchange of chloride ions with various important carboxylate anions through phospholipid membranes.
- Simple changes made to the structure of these receptors altered their selectivity in transporting lactate and pyruvate.
- This discovery highlights the potential of thiourea receptors in controlling ion transport across cell membranes, which is relevant for biological processes.
Article Abstract
A series of neutral thiourea receptors were found to mediate the antiport of chloride with a range of biologically relevant carboxylate anions across phospholipid bilayers. Simple structural modification of the carriers resulted in a change in the lactate/pyruvate transport selectivity.
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| http://dx.doi.org/10.1039/c2cc37468d | DOI Listing |
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