Rapid detection of Campylobacter antigen by enzyme immunoassay leads to increased positivity rates.

J Clin Microbiol

David Geffen School of Medicine, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, California, USA.

Published: February 2013

Campylobacter antigen detection by enzyme immunoassay (EIA) provides rapid results compared to traditional culture. However, concern exists regarding specificity. Verification studies of an EIA compared to culture revealed a positive predictive value (PPV) of 91%, whereas PPV fell to 42% during routine diagnostic testing. We suggest all positive EIA results be confirmed via culture.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553896PMC
http://dx.doi.org/10.1128/JCM.02565-12DOI Listing

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