Direct amide formation using radiofrequency heating.

Org Biomol Chem

School of Chemistry & Chemical Engineering, Queens University Belfast, Stranmillis Road, Belfast, BT9 5AG, UK.

Published: July 2013

We present a simple method for direct and solvent-free formation of amides from carboxylic acids and amines using radiofrequency heating. The direct energy coupling of the AC magnetic field via nickel ferrite magnetic nanoparticles enables fast and controllable heating, as well as enabling facile work-up via magnetic separation.

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Source
http://dx.doi.org/10.1039/c2ob26930aDOI Listing

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