In poisonings during pregnancy, the mother should be treated as well as possible, following the general principles and regimes utilized in treatments for poisoning. Activated charcoal can be used safely. In cases where administration of antidote is justified from the mother's standpoint, it can also be given to a pregnant mother. Risk assessment for poisonings during pregnancy can be difficult in individual cases. Fetal prognosis is, however, relatively good provided that the mother receives appropriate and timely initiated treatment.
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Vet Res Commun
January 2025
Department of Veterinary Medicine, University of Perugia, Via San Costanzo, 4, Perugia, 06126, Italy.
This study describes the congenital goiter in an alpaca (Vicugna pacos) fetus aborted in November 2021 with the clinical and pathological findings in the dam that was found dead on the farm three weeks after a miscarriage. The dam was a black coat alpaca bred in the Netherlands, imported in Italy in January 2021, and housed in a farm of central Italy for breeding purposes. Signalment and clinical data on dam and fetus were collected from the farmer and referring veterinarian.
View Article and Find Full Text PDFBMJ Open
January 2025
Vanke School of Public Health, Tsinghua University, Beijing, China
Objectives: This study investigated the autopsy rate of hospital deaths in Shenzhen megacity and identified factors that may impact the decision to perform an autopsy in hospital deaths.
Design: This is a population-based retrospective cohort study.
Setting: Shenzhen is a megacity in China with a population of more than 17 million and a total of 151 hospitals.
Toxins (Basel)
November 2024
Department of Obstetrics and Gynecology, Semmelweis University, 1088 Budapest, Hungary.
The effect of mycotoxin exposure on follicular fluid composition and reproductive outcomes in women undergoing in vitro fertilisation (IVF) was investigated in this study. Twenty-five patients were included, and follicular fluid and serum samples were analysed for various mycotoxins. Principal observations:1.
View Article and Find Full Text PDFLancet Reg Health Eur
December 2024
School of Health and Wellbeing, University of Glasgow, UK.
Background: Socioeconomic inequality in infant mortality in the UK is rising. This study aims to identify contributory maternal and pregnancy factors that can explain the known association between area deprivation and infant mortality.
Methods: A cohort study was conducted using Clinical Practice Research Datalink (CPRD) primary care data between 2004 and 2019 linked to the Index of Multiple Deprivation (IMD), and infant mortality from the Office for National Statistics death data.
J Cell Mol Med
December 2024
Department of Critical Care Medicine, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, P. R. China.
Sevoflurane's potential impact on cognitive function and neurodevelopment, especially in susceptible populations such as infants and the elderly, has raised widespread concern. This study focuses on how sevoflurane induces ferroptosis in astrocytes and identifies solute carrier family 7 member 11 (SLC7A11) as a mediator of ferroptosis, providing new insights into sevoflurane-related neurotoxic pathways. We analysed single-cell sequencing (scRNA-seq) data from sevoflurane-exposed mice and control mice, supplemented with bulk RNA-seq data, to assess gene expression alterations.
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