AI Article Synopsis
- Interferon gamma releasing assays like QuantiFERON-TB Gold (QFT-G) are recommended alongside the tuberculin skin test (TST) for better detection of latent tuberculosis infection (LTBI), especially before immunosuppressive therapy.
- A 52-year-old woman with rheumatoid arthritis developed peritoneal tuberculosis after testing negative for TB before starting infliximab, highlighting the limitations of these tests in immune-compromised individuals.
- After her symptoms progressed and TST and QFT-G were retested, both came back positive, leading to a diagnosis of peritoneal TB, which was successfully treated with anti-TB medication.
Article Abstract
Recently, interferon gamma releasing assay has been recommended to compensate the tuberculin skin test (TST) for screening for latent tuberculosis infection (LTBI). Although it improved the detection of LTBI before treatment with tumor necrosis factor blocker, its application to immune suppressed patients is limited. We report a case of peritoneal tuberculosis (TB) developed in a patient who tested positive for TST and QuantiFERON-TB Gold (QFT-G) before infliximab therapy, to emphasize the importance of monitoring during treatment. A 52-year-old woman presented with abdominal distension. She had been diagnosed with seropositive rheumatoid arthritis six years ago. She had started taking infliximab six months ago. All screening tests for TB were performed and the results of all were negative. At admission, the results of repeated TST and QFT-G tests were positive. Histopathological examination confirmed peritoneal TB. The patient started anti-TB therapy and the symptoms were relieved.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492425 | PMC |
| http://dx.doi.org/10.4046/trd.2012.73.4.234 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A union of two rare pathologies: small bowel diverticula perforation secondary to impacted gallstone ileus.
J Surg Case Rep
January 2025
Department of Colorectal Surgery, Sydney Adventist Hospital, 185 Fox Valley Road, Wahroonga, Sydney, New South Wales 2076, Australia.
An 84-year-old lady presented with 1 day history of sudden onset generalized abdominal pain, fevers, and peritonism. Computed tomography was suggestive of a mid-small bowel perforation associated with a distal ovoid soft tissue density structure without pneumobilia. An urgent laparotomy demonstrated two areas of jejunal diverticula necrosis and perforation associated with a 3 cm luminal mass in the proximal ileum, and proximal small bowel dilatation.
View Article and Find Full Text PDFA Rare Case of Infective Endocarditis Caused by .
J Community Hosp Intern Med Perspect
January 2025
Department of Cardiology, Long Island Community Hospital, United States.
is an alpha-hemolytic gram-positive catalase-negative coccus that typically causes urinary tract infections. It has been rarely implicated in other invasive infections such as endocarditis, bacteremia, peritonitis, meningitis, and vertebral osteomyelitis. There are approximately 50 reported cases of infective endocarditis in literature.
View Article and Find Full Text PDFO157 induced spontaneous bacterial peritonitis in pregnancy.
BMJ Case Rep
January 2025
Obstetrics and Gynecology, All India Institute of Medical Sciences Bhopal, Bhopal, Madhya Pradesh, India.
Bladder rupture in late-pregnancy mares: Four cases.
J Equine Vet Sci
January 2025
Clinique Vétérinaire Équine du Harfang, Varennes, Quebec, Canada.
This case series reports four late pregnancy broodmares that were diagnosed with bladder rupture. The initial presentations were abdominal discomfort (n = 3) and dystocia (n = 1). All mares (n = 4) were overdue or at their expected time of delivery.
View Article and Find Full Text PDFDirect-Acting Antivirals in Hepatitis C Treatment for Renal Impairment: Liver Safety Concerns and Effectiveness in Peritoneal Dialysis.
Biomedicines
December 2024
Master Program in Clinical Pharmacy, School of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Glecaprevir/pibrentasvir (G/P) and elbasvir/grazoprevir (EBR/GZR) are effective treatments for chronic hepatitis C (CHC), especially in patients with chronic kidney disease (CKD). However, both regimens carry a risk of drug-induced liver injury (DILI). This study investigates the association between renal failure and DILI, using real-world data, and assesses the effectiveness of these treatments in peritoneal dialysis patients.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!