The purpose of this paper is to describe a case of juvenile cystic adenomyoma in a 17 year-old female patient with severe dysmenorrhoea unresponsive to non-steroidal anti-inflammatory drugs. The patient presents progressively worsening dysmenorrhoea that started 2 years after menarche and a cystic uterine lesion in MRI. The cyclic nature of symptoms, the similarity of the lesion and endometrium in MRI signal intensity and response to hormone suppression are consistent with juvenile cystic adenomyoma. The treatment depends on the age of the patient, severity of her symptoms and size and localisation of the cyst. This is a rare condition in young nulliparous women with a challenging differential diagnosis. This case highlights the relevance of MRI in the patient's study, featuring important characteristics of the lesion that disclosed the final diagnosis.
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http://dx.doi.org/10.1136/bcr-2012-007006 | DOI Listing |
CMAJ
January 2025
Patient partner (Bleskie), Ottawa, Ont.; Montreal Clinical Research Institute (Rabasa-Lhoret); Division of Endocrinology and Metabolism (Rabasa-Lhoret), Department of Medicine and Nutrition, Faculty of Medicine, Université de Montréal, Montréal, Que.; Division of Endocrinology and Metabolism (Sun), Department of Medicine, The Ottawa Hospital, University of Ottawa, Ottawa Hospital Research Institute, Ottawa, Ont.
Eur J Ophthalmol
December 2024
Ophthalmology Department, Hospital Universitario La Paz, Madrid, Spain.
X-linked retinoschisis (XLRS) is an inherited retinal disorder due to mutations in retinoschisin 1, characterized by impaired central vision secondary to parafoveal cystic cavities and visual field loss by splitting through the retinal nerve fibre layer in the peripheral retina. It is the leading cause of juvenile macular degeneration in males, and currently there is no approved treatment but carbonic anhydrase inhibitors can be used. A retrospective review of the medical records of 17 children with confirmed XLRS seen in the Paediatric Ophthalmology Department of La Paz University Hospital from the 1st of January 2009 to the 1st of June of 2023 was conducted.
View Article and Find Full Text PDFJ Pediatr Gastroenterol Nutr
January 2025
Department of Paediatric Gastro-Enterology, KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel (VUB), Brussels, Belgium.
Handgrip strength (HGS) is a simple measurement of maximum voluntary muscle strength and is widely used as a single indicator of overall muscle strength. This systematic review summarized the evidence about the relation between HGS and health outcomes in hospitalized children or chronically ill children. The primary outcome was the number of hospital days in a 2-month period for outpatients and the length of hospital stay for inpatients.
View Article and Find Full Text PDFDiabetologia
November 2024
Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
Aims/hypothesis: We aimed to analyse TrialNet Anti-CD3 Prevention (TN10) data using oral minimal model (OMM)-derived indices to characterise the natural history of stage 2 type 1 diabetes in placebo-treated individuals, to describe early metabolic responses to teplizumab and to explore the predictive capacity of OMM measures for disease-free survival rate.
Methods: OMM-estimated insulin secretion, sensitivity and clearance and the disposition index were evaluated at baseline and at 3, 6 and 12 months post randomisation in placebo- and teplizumab-treated groups, and, within each group, in slow- and rapid-progressors (time to stage 3 disease >2 or 2 years). OMM metrics were also compared with the standard AUC C-peptide.
Jpn J Ophthalmol
November 2024
Department of Ophthalmology, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, 573-1191, Osaka, Japan.
Purpose: To clarify the clinical and pathologic findings of 7 patients with inflamed juvenile conjunctival nevus (IJCN) treated with tacrolimus.
Study Design: Retrospective study.
Subjects And Methods: The medical records of 7 male patients diagnosed with IJCN between February 2007 and October 2022 at the Kansai Medical University Hospital and Ideta Eye Hospital were retrospectively reviewed.
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