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Seasonal shifts in respiratory pathogen co-infections and the associated differential induction of cytokines in children.
Cytokine
February 2025
Center for Translational Medicine, Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei 430023, China; Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. Electronic address:
In the post-pandemic era, research on respiratory diseases should refocus on pathogens other than the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Respiratory pathogens, highly infectious to children, with to different modes of infection, such as single-pathogen infections and co-infections. Understanding the seasonal patterns of these pathogens, alongside identifying single infections and co-infections and their impact on the pediatric immune status, is crucial for clinical diagnosis, treatment, and prognosis in children.
View Article and Find Full Text PDFThe Discovery of Head Direction Cells: A Personal Account.
Hippocampus
January 2025
Department of Psychological & Brain Sciences, Dartmouth College, Hanover, USA.
This article is my recollection of events surrounding the discovery of head direction (HD) cells by Jim Ranck in 1984 and the first journal publications 6 years later. Ranck first described the fundamental properties of HD cells qualitatively in a Society for Neuroscience abstract (1984) and in the proceedings to a conference. Ranck, however, was convinced by Bob Muller, a faculty colleague in the lab, to delay writing up Jim's discovery until they developed a two-spot video tracking system, which would enable proper quantitative analyses.
View Article and Find Full Text PDFA fast thermal desorption unit for micro thermal desorption tubes, Part II: Method development and validation for explosives and chemical warfare agent simulants.
J Chromatogr A
January 2025
Institute of Nutritional and Food Sciences, University of Bonn, Friedrich-Hirzebruch Allee 5, D-53115 Bonn, Germany; HyperChrom Deutschland GmbH, Konrad-Zuse-Strasse 3, 53347 Alfter, Germany. Electronic address:
A thermal desorption FF-TG-GC/MS method with a cycle time of just 164s including cryofocusing, thermal desorption, analyte separation and system cool down was developed for the analysis of ten explosives and six chemical warfare agent (CWA) simulants. Sampling was carried out both in liquid and gaseous form using micro thermal desorption tubes (μTD-tubes, 1.4mm I.
View Article and Find Full Text PDFArticle Synopsis
- Balancing speed and accuracy is difficult in 3D reconstruction, as one-shot structured light can scan quickly but often produces low-quality 3D point clouds in areas with significant height changes.
- The authors propose a new reconstruction method using shearlet transform, which improves accuracy by combining spatial and frequency information.
- Their approach involves obtaining coefficients from a deformed fringe pattern, selecting the largest values for filtering, and generating quality maps to guide a more reliable phase unwrapping process, leading to improved accuracy in challenging regions.
Is it Time to Refocus the Role of the CDC?
JAMA Health Forum
October 2024
American Enterprise Institute, Washington, DC.
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