Mice and guinea pigs were immunized with the haemagglutinin (HA) of influenza B-USSR/100 virus, either in Syntex Adjuvant Formulation-1 (SAF-1) or in saline. Antibody titres were determined by ELISA, haemagglutination inhibition and virus neutralization. Animals immunized with HA in SAF-1 had significantly higher antibody titres than did animals immunized with HA in saline. Both 3-week-old and 13 1/2-month-old mice had greater and more uniform antibody responses to HA in SAF-1 than to HA in saline.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0264-410x(90)90177-n | DOI Listing |
Publication Analysis
Top Keywords
antibody responses
8
saf-1 saline
8
antibody titres
8
animals immunized
8
enhancement antibody
4
responses influenza
4
influenza virus
4
virus haemagglutinin
4
haemagglutinin adjuvant
4
adjuvant formulation
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!