Introduction: Sleepiness is one of the cardinal complaints of patients in tertiary referral centres for sleep disorders. It is commonly associated with sleep disorders, but the additional influence of obesity remains unclear. We hypothesised that obesity may be an independent predictor of sleepiness in this population.
Patients And Methods: We reviewed 335 patients undergoing overnight polysomnography over a 3 month period (May-July 2011), recording selected sleep parameters in addition to subjective sleepiness as measured by the Epworth Sleepiness Scale (ESS, 0-24 points).
Results: 173 patients (120 male, age 52 (13) years, BMI 33.9 (7.4) kg/m(2)) had obstructive sleep apnoea and 59 of those were established on continuous positive airway pressure (CPAP). 55 patients (38 male, age 56 (14) years, BMI 31.7 (6.7) kg/m(2)) had PLM disorder, with 3 on medical treatment. 155 patients were obese (93 male, age 50 (14) years, BMI 37.3 (6.1) kg/m(2)) and this group was significantly sleepier than the 180 non-obese subjects (107 male, age 42 (15) years, BMI 25.3 (3.0) kg/m(2)). The mean ESS of the obese group was 12.9 (5.5) points, compared to 10.4 (5.7) points for the non-obese patients (p < 0.001). Those with a diagnosis of OSA had an ESS of 12.3 (5.8) versus 10.7 (5.7) points for those without (p = 0.007). Females had an ESS of 12.8 (5.9) compared to 10.7 (5.5) points for male patients (p < 0.001). Regression analysis revealed that obesity (p = 0.007), PLM disorder (p = 0.010) and hypertension (p = 0.032) were independently associated with subjective sleepiness (adjusted R(2) = 0.384, p = 0.02), obesity accounting for 15.7% of the variability in sleepiness.
Conclusion: Independent of underlying sleep disorders, obesity contributes significantly to daytime sleepiness. Measures to promote weight loss and close links to a dietician assisted service will be helpful in the specialist setting of a sleep disorders service to improve long-term health outcomes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.rmed.2012.10.013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
No Association Between Donor Variables and Clinically Significant Outcomes, Reoperations, and Failure After Osteochondral Allograft Transplantation.
Am J Sports Med
January 2025
Midwest Orthopaedics at Rush University Medical Center, Chicago, Illinois, USA.
Background: Mismatch between osteochondral allograft (OCA) donor and recipient sex has been shown to negatively affect outcomes. This study accounts for additional donor variables and clinically relevant outcomes.
Purpose: To evaluate whether donor sex, age, donor-recipient sex mismatch, and duration of graft storage affect clinical outcomes and failure rates after knee OCA transplantation.
Exploring Chronic Pain in Hemodialysis Patients: An Observational Study Based on the New IASP Classification for ICD-11.
Pain Ther
January 2025
Department of Medicine, Nephrology Division, University of Verona, Verona, Italy.
Introduction: Pain is one of the most frequently reported symptoms in hemodialyzed (HD) patients, with prevalence rates between 33% and 82%. Risk factors for chronic pain in HD patients are older age, long-lasting dialysis history, several concomitant diseases, malnutrition, and others. However, chronic pain assessment in HD patients is rarely performed by specialists in pain medicine, with relevant consequences in terms of diagnostic and treatment accuracy.
View Article and Find Full Text PDFEffectiveness of a protocol with antimicrobial photodynamic therapy for treating osteoradionecrosis: a retrospective study.
Support Care Cancer
January 2025
Dentistry Department, Barretos Cancer Hospital, Barretos, São Paulo, Brazil.
Objective: To compare the treatment of osteoradionecrosis (ORN) using a protocol that incorporates antimicrobial photodynamic therapy with a conventional treatment protocol.
Methodology: This retrospective study analyzed 55 patients diagnosed with ORN at a reference hospital between 2002 and 2021. Patients were treated using two different clinical protocols.
Medical & Socioeconomic Risk Factors Associated with Lack of Neurodevelopmental Evaluation Following Neonatal Cardiac Surgery.
Pediatr Cardiol
January 2025
Division of Cardiac Critical Care, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Neonates with congenital heart disease (CHD) who undergo cardiopulmonary bypass (CPB) are at high-risk for unfavorable neurodevelopmental (ND) outcomes and are recommended for ND evaluation (NDE); however, poor rates have been reported. We aimed to identify risk factors associated with lack of NDE. This single-center retrospective observational study included neonates < 30 days old who underwent CPB and survived to discharge between 2012 and 2018.
View Article and Find Full Text PDFDental maxillary sinus pathology: a CBCT-based case-control study.
Odontology
January 2025
Division of Oral Radiology, Faculdade São Leopoldo Mandic, Rua Dr. José Rocha Junqueira 13 Campinas, São Paulo, 13045-755, Brazil.
This study evaluated the association between dental infection and maxillary sinus pathology, and the influence of age, sex, type of tooth, root proximity to the sinus floor, the condition of the primary maxillary ostium, and the presence of an accessory maxillary ostium in this process. Computed Tomography scans were selected, and upper posterior teeth were evaluated for the presence of apical periodontitis (AP), bone loss with furcation involvement, and endoperiodontal lesion (EPL), subsequently, sinuses were evaluated for mucosal thickening (MT) and opacification of the maxillary sinus (OMS). Logistic regression models were constructed, and Chi-squared and Fisher's tests were applied.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!