Chemical composition and biological activities of essential oil from Hyptis crenata growing in the Brazilian cerrado.

Nat Prod Commun

Centro de Cidncias Exatas e Tecnologia, Universidade Federal de Mato Grosso do Sul, Av. Senador Filinto Muller 1555, Campo Grande, MS 79074-460, Brazil.

Published: October 2012

AI Article Synopsis

  • * The essential oil was tested against various fungal and bacterial strains, showing the strongest activity against Staphylococcus aureus, Enterococcus faecalis, Cryptococcus neoformans, and Candida species.
  • * Additionally, the oil demonstrated significant anti-tick properties, inhibiting 94.4% of oviposition in Rhipicephalus (Boophilus) microplus at a concentration of 2.5% during in vivo tests.

Article Abstract

Essential oils from species of the genus Hyptis are well-known for their significant biological properties, including antimicrobial and acaricidal activities. The essential oil from the aerial parts of H. crenata was obtained by hydrodistillation; bomeol (17.8%), 1,8-cineol (15.6%) and p-cimene (7.9%) were characterized by GC-MS as its major constituents. The essential oil was evaluated in vitro for its antimicrobial activities against six fungal and five bacterial strains, by measuring the respective MICs, MFCs and MBCs, using broth microdilution methods. The strongest bactericidal activities were shown against Staphylococcus aureus and Enterococcus faecalis, while the strongest fungicidal activities were against Cryptococcus neoformans, Candida glabrata and Candida tropicalis. The oil was also assessed for its anti-tick properties and, at a concentration of 2.5%, it significantly inhibited in vivo oviposition of engorged females of the cattle tick Rhipicephalus (Boophilus) microplus, using the adult immersion test., with an effectiveness of 94.4%.

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