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Melanoma: Assessment and Management summary of 2022 update of the NICE guidelines.
Br J Dermatol
January 2025
Research fellow and General surgery trainee, Royal Marsden Hospital, London, UK.
Melanoma is the fifth most common skin cancer in the UK, accounting for 4% of all new cancer cases, with a predicted 7% increase in incidence between 2014-35. In parallel, since the initial publication of the Melanoma NICE Guidelines in 2015, there has been a paradigm shift in the management of the disease, with the introduction of effective systemic therapies. These innovations have reshaped the management of melanoma throughout the patient journey, and improved clinical outcomes.
View Article and Find Full Text PDFOutcomes of extremely preterm infants who participated in a randomised trial of dopamine for treatment of hypotension (the HIP trial) at 2 years corrected age.
Arch Dis Child Fetal Neonatal Ed
January 2025
Department of Paediatrics and Child Health, INFANT Centre, University College Cork, Cork, Ireland
Objective: To determine survival and neurodevelopmental outcomes in the Hypotension in Preterm (HIP) trial.
Design: Prospective follow-up of infants enrolled in randomised controlled trial.
Participants: 58 infants born before 28 weeks of gestation with low mean arterial blood pressure.
Morphometric evaluation of middle ear anatomical structures using full volume (12 × 9) CBCT scans: A retrospective study in Navi Mumbai.
Natl J Maxillofac Surg
November 2024
Department of Oral Medicine and Maxillofacial Radiology, Dr. G. D. Pol Foundations YMT Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Introduction: The tympanic cavity contains three tiny bones, the malleus, incus, and stapes, which have a fundamental role in the transmission of sound. Recent research emphasizes the use of CBCT for the anatomic study of the temporal bone. The information about middle ear anatomy on CBCT scans is meager; hence, this retrospective study was conducted to identify and determine the various morphometrical parameters of the malleus using CBCT which can be helpful during reconstructive procedures for the otologic surgeon.
View Article and Find Full Text PDFComparison of surgical wound infection and dehiscence following the use of two methods of nylon sutures and skin staples in staples in diabetic mellitus patients undergoing total knee arthroplasty surgery: a randomized clinical trial study.
BMC Musculoskelet Disord
January 2025
Department of Operating Room Technology, Community based psychiatric care research center, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz-Iran, Nemazee Square, Shiraz, 71936-13119, Iran.
Objective: Timely and complete surgical wound healing substantially affects the patient's performance and satisfaction with surgery outcomes. Sutures and staples are two common wound closure methods in total knee arthroplasty; however, their role in reducing the rate of surgical wound infections and dehiscence in diabetic patients is unclear. Therefore, this study was conducted to investigate the rate of infection and post-closure dehiscence in wounds closed with either nylon sutures or skin staples in diabetic patients undergoing total knee arthroplasty (TKA).
View Article and Find Full Text PDFLong-Term Survival Following Coronary Artery Bypass Graft Surgery.
Ann Thorac Surg
January 2025
Center for Innovation and Outcomes Research, Department of Surgery, Columbia University New York, NY; Columbia HeartSource, Department of Surgery, Columbia University, New York, NY; Division of Cardiac, Thoracic and Vascular Surgery, Columbia University, New York, NY. Electronic address:
Background: Management guidelines for stable three-vessel coronary artery disease have become a subject of debate. We aim to provide a benchmark for the survival of patients with normal ejection fraction, stable three-vessel disease, and elective coronary artery bypass graft (CABG) surgery.
Methods: Data from consecutive patients with normal ejection fraction undergoing elective primary isolated CABG for triple-vessel disease in a diverse 11-center surgical network between 2008 and 2020 were analyzed.
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