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The safety and efficacy of applying a high-current temporal interference electrical stimulation in humans.
Front Hum Neurosci
November 2024
School of Mental Health, Bengbu Medical University, Bengbu, China.
Background: Temporal interference electrical stimulation (TI) is promise in targeting deep brain regions focally. However, limited electric field intensity challenges its efficacy.
Objective: This study aimed to introduce a high-current TI electrical stimulation protocol to enhance its intensity and evaluate its safety and efficacy when applied to the primary motor cortex (M1) in the human brain.
Postoperative Nodal Efficiency of the Lesional-Hemispheric Hand Motor Area Increasing Potentially Facilitated Motor Recovery for SMA Syndrome.
CNS Neurosci Ther
November 2024
Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Background: Supplementary motor area (SMA) syndrome commonly occurs after glioma resection and requires weeks to months of recovery.
Methods: Thirty-four glioma patients with SMA syndrome were reviewed and assigned to recovered and non-recovered groups based on whether their motor function recovered on postoperative day 7. To validate the association between variations in nodal properties and recovery time, neuro-navigated repetitive transcranial magnetic stimulation (nrTMS) was applied to stimulate potential nodes.
Deep brain stimulation for Tourette's syndrome.
Cochrane Database Syst Rev
August 2024
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the efficacy and harm of deep brain stimulation for motor symptoms, with psychiatric and behavioural comorbidities, either individually or in combination, in adults and adolescents with Tourette's syndrome compared to placebo, sham intervention, or the best available behavioural and pharmacological treatment.
View Article and Find Full Text PDFEffectiveness of Intermittent Theta Burst Stimulation to Enhance Upper Extremity Recovery After Stroke: A Pilot Study.
Arch Phys Med Rehabil
October 2024
Department of Neurology, Bakırkoy Prof Dr Mazhar Osman Training and Research Hospital for Psychiatric, Neurologic and Neurosurgical Diseases, Istanbul Health Sciences University, Istanbul.
Objectives: To first investigate the effectiveness of modified constraint-ınduced movement therapy (mCIMT) in low-functioning patients with stroke (PwS). Second, we aimed to investigate the efficiency of intermittent theta-burst stimulation (iTBS), applied on intermittent days, in addition to the mCIMT in PwS.
Design: A randomized, sham-controlled, single-blinded study.
Neutralization of Interleukin 1-beta is associated with preservation of thalamic capillaries after experimental traumatic brain injury.
Front Neurol
April 2024
Translational Neurology Group, Department of Clinical Science, Wallenberg Neuroscience Center and Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.
Introduction: Traumatic brain injury to thalamo-cortical pathways is associated with posttraumatic morbidity. Diffuse mechanical forces to white matter tracts and deep grey matter regions induce an inflammatory response and vascular damage resulting in progressive neurodegeneration. Pro-inflammatory cytokines, including interleukin-1β (IL-1β), may contribute to the link between inflammation and the injured capillary network after TBI.
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