Sequential activation of different reversible exchange reactions in a dynamic combinatorial library allows directed exploration of the chemical space: initially a macrocyclic scaffold is selected by the template and finally side chain and conformational constrains are introduced into such a scaffold.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol3027335 | DOI Listing |
Publication Analysis
Top Keywords
dynamic combinatorial
8
combinatorial library
8
two-stage amplification
4
amplification receptors
4
receptors multilevel
4
multilevel orthogonal/simultaneous
4
orthogonal/simultaneous dynamic
4
library sequential
4
sequential activation
4
activation reversible
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!