Epidemiology of sebaceous carcinoma in Alberta, Canada, from 1988 to 2007.

J Cutan Med Surg

Division of Dermatology and Cutaneous Sciences, Department of Medicine, University of Alberta, Edmonton, AB.

Published: April 2013

AI Article Synopsis

  • The study investigated the trends in sebaceous carcinoma (SC) in Alberta, Canada, from 1988 to 2007, revealing a significant rise in incidence.
  • The age-standardized incidence of SC grew from 0.22 to 0.65 per 100,000, mainly affecting the elderly, with over 85% of cases in individuals aged 60 and older.
  • The most common site for SC was the face (37.7%), and there were notable gender differences in both the prevalence and anatomical distribution of the cancer.

Article Abstract

Background: The epidemiology of sebaceous carcinoma (SC) has not previously been examined in a Canadian population.

Objective: To determine the epidemiologic trends of SC in Alberta, Canada, from 1988 to 2007.

Methods: This study was a population-based, retrospective, epidemiologic analysis of SC in Alberta over a 20-year span.

Results: Over the study period, the age-standardized SC incidence increased from 0.22 per 100,000 to 0.65 per 100,000. Sebaceous carcinoma is a cancer that predominantly affects the elderly (over 85% of cases were in persons 60 years or older). Interestingly, the face (37.7% of cases), not the eyelids (26.2% of cases), was the most frequently affected site overall. Gender-specific trends reflected a slight male predominance (1.4:1) and significant differences in anatomic distribution between the sexes.

Conclusion: For unexplained reasons, there has been a threefold increase in SC incidence in Alberta over the last two decades. In addition, there are significant gender-specific differences in the anatomic distribution of SC.

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Source
http://dx.doi.org/10.1177/120347541201600610DOI Listing

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