We describe a case of methaemoglobinaemia (MtHb) in a previously healthy 39-year-old gentleman who presented with a traumatic glass laceration to his right wrist that required emergency surgery to control bleeding and repair his ulnar artery. The MtHb was noted on blood gas analysis by the anaesthetist after the patient had a drop in arterial oxygen saturation under general anaesthetic. We initially suspected the lidocaine local anaesthetic injected proximal to his wound for pain control in the emergency department an hour preoperatively, but then discovered that the patient was a recreational user of 'poppers' and had in fact been using these drugs just before his injury and hospitalisation. The patient's condition stabilised overnight with conservative management. Given how commonly hand surgeons and other clinical staff use local anaesthetics, we reviewed the literature on this uncommon, but potentially fatal, complication, its causes and evidence-based management.
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http://dx.doi.org/10.1136/bcr-2012-007196 | DOI Listing |
Trop Med Infect Dis
December 2024
Evolutionary Ecology Group, Department of Biology, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, Wilrijk, 2610 Antwerp, Belgium.
is a vector of , the causative agent of cutaneous leishmaniasis. This study assessed the abundance and distribution of in different habitats and human houses situated at varying distances from hyrax (reservoir host) dwellings, in Wolaita Zone, southern Ethiopia. Sandflies were collected from January 2020 to December 2021 using CDC light traps, sticky paper traps, and locally made emergence traps.
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December 2024
State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and KLMDASR of Tianjin, Nankai University, Tongyan Road, Haihe Education Park, Tianjin, 300350, China. Electronic address:
J Neuropathol Exp Neurol
January 2025
School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan (R.O.C.).
Neuropathic pain arises as a consequence of injury or disease in the peripheral or central nervous system. Clinical cases have shown that spine postoperative chronic neuropathic pain remains a troublesome issue in medical treatment due to the presence of various degrees of peridural fibrosis and different inflammatory factors after spinal surgery. To address this issue, we developed a new neuropathic mice model that successfully simulates the real clinical situation by applying oxidative regenerative cellulose to L5 DRG (dorsal root ganglion).
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