AI Article Synopsis
- The study aimed to assess how effective bupivacaine is for relieving pain after tonsillectomy within the first day.
- Conducted at King Abdulaziz University Hospital, the research involved 35 patients who received a tonsillectomy; one side used bupivacaine while the other used a saline solution as a control.
- Results showed that while pain reduction wasn't significant in the early hours, there was a notable decrease in pain levels at 6, 12, and 24 hours after surgery, indicating that bupivacaine may be beneficial for post-operative pain management.
Article Abstract
Objective: To evaluate the effectiveness of bupivacaine as topically applied in reducing post tonsillectomy pain within the first 24 hours.
Methods: This prospective, randomized, placebo-controlled, intra-individual, single-blind study was conducted at the Otolaryngology Department, King Abdulaziz University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia from October 2009 until March 2010. Thirty-five patients underwent cold knife tonsillectomy. One tonsillar fossa was packed with gauze soaked in plain 0.25% bupivacaine, while the other tonsillar fossa was packed with gauze soaked in normal saline (the control side). Both gauzes were applied for 5 minutes. The patients' pain was evaluated on each side using the visual analog scale at 2, 4, 6, 12, and 24 hours post-operatively.
Results: The reduction in pain at 2 and 4 hours was statistically insignificant compared with the control side. However, at 6, 12, and 24 hours post operatively, the reduction of pain was statistically significant.
Conclusion: Topical application of bupivacaine at a 0.25% concentration appears to a considerable degree of analgesia within the first 24 hours post tonsillectomy.
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