Imaging of complications of liver transplantation: multidetector computed tomography findings.

Transplant Proc

Department of Computed Tomography and Magnetic Resonance Imaging, "G. Papanikolaou" General Hospital, Thessaloniki, Greece.

Published: November 2012

Background: Liver transplantation is the treatment of choice for patients with end-stage liver disease; however, it is associated with a multitude of postoperative complications. Herein we have presented our experience with the application of multidetector computed tomography (MDCT) in the follow-up of liver transplant recipients.

Patients And Methods: Twenty-four liver transplantation patients were examined with triphasic hepatic computed tomography. Both symptomatic and asymptomatic patients were included in the study. Examinations were performed using a multidetector scanner.

Results: We documented seven cases of thrombosis, three stenosis, and two hepatic artery (HA) aneurysms. Portal vein (PV) stenosis and PV thrombosis were observed in two cases each. We observed one case of synchronous HA and PV stenosis; one inferior vena cava (IVC) and left renal vein thrombosis, and one IVC thrombosis. In three cases of HA obstruction we observed transplant neovascularization. One HA obstruction and one HA stenosis were accompanied by bilomas. Finally, we discovered three cases of hepatocellular carcinoma.

Conclusion: In our experience MDCT as a single noninvasive examination, was a sensitive means to detect and evaluate vascular complications after liver transplantation, offering adequate information concerning the liver parenchyma, the rest of the abdomen, and to a lesser extent the biliary tract.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.transproceed.2012.09.015DOI Listing

Publication Analysis

Top Keywords

liver transplantation
16
computed tomography
12
complications liver
8
multidetector computed
8
thrombosis three
8
three cases
8
liver
7
imaging complications
4
transplantation
4
transplantation multidetector
4

Similar Publications

Background: Helicobacter pylori bacteria colonize the gastric mucosa and contribute to the occurrence and development of gastrointestinal diseases. According to the WHO, H. pylori bacteria are considered class I carcinogen.

View Article and Find Full Text PDF

Background: Larsucosterol is a DNA methyltransferase inhibitor in development for alcohol-associated hepatitis (AH), a disease for which there is no approved therapy.

Methods: In this phase 2b trial, patients with severe AH were randomly assigned 1:1:1 to receive 30 mg or 90 mg of larsucosterol or placebo; a second dose was administered after 72 hours if the patient remained hospitalized. All patients received supportive care as determined by investigators.

View Article and Find Full Text PDF

Hepatopulmonary syndrome (HPS) and portopulmonary hypertension (POPH) are two distinct pulmonary vascular complications seen in patients with liver disease and/or portal hypertension. HPS is characterized by disturbed gas exchange and hypoxemia because of intrapulmonary vascular dilatations. POPH is defined by pulmonary arterial hypertension, which might lead to right heart failure.

View Article and Find Full Text PDF

Comparative dissection of transcriptional landscapes of human iPSC-NK differentiation and NK cell development.

Life Med

August 2024

The Bone Marrow Transplantation Center of The First Affiliated Hospital &Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou 310012, China.

Clinical and preclinical research has demonstrated that iPSC-derived NK (iNK) cells have a high therapeutic potential, yet poor understanding of the detailed process of their differentiation and their counterpart cell development has hindered therapeutic iNK cell production and engineering. Here we dissect the crucial differentiation of both fetal liver NK cells and iNK cells to enable the rational design of advanced iNK production protocols. We use a comparative analysis of single-cell RNA-seq (scRNA-seq) to pinpoint key factors lacking in the induced setting which we hypothesized would hinder iNK differentiation and/ or functionality.

View Article and Find Full Text PDF

Laparoscopic hepatectomy using indocyanine green attenuates postoperative inflammatory response for hepatocellular carcinoma: A propensity score matching analysis.

World J Gastrointest Surg

January 2025

Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

Background: Improving the intraoperative and postoperative performance of laparoscopic hepatectomy was quite a challenge for liver surgeons.

Aim: To determine the benefits of indocyanine green (ICG) fluorescence imaging in patients with hepatocellular carcinoma (HCC) who underwent laparoscopic hepatectomy during and after surgery.

Methods: We retrospectively collected the clinicopathological data of 107 patients who successfully underwent laparoscopic hepatectomy at Zhongshan Hospital (Xiamen), Fudan University from June 2022 to June 2023.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!