This year, 2012, marks the 100th anniversary of Captain Scott his reaching the South Pole and of his death on the return journey. There has been much discussion on the cause of death of Scott and his colleagues and, in particular, whether he died of scurvy. There has probably been even more discussion on the cause of death of Edgar Evans, one of Scott's companions. This paper reviews the topic.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1258/jmb.2011.011039 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The biological intersection between chemotherapy-related cognitive impairment and Alzheimer's disease.
Am J Pathol
January 2025
Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Alzheimer's disease (AD) is the most common type of dementia and one of the leading causes of death in elderly patients. The number of patients with AD in the United States is projected to double by 2060. Thus, understanding modifiable risk factors for AD is an urgent public health priority.
View Article and Find Full Text PDFDecoding the SARS-CoV-2 Infection Process: Insights into Origin, Spread, and Therapeutic Approaches.
Microb Pathog
January 2025
Department of Bioengineering, Faculty of engineering, Integral University, Lucknow-226026, India. Electronic address:
Globally, over 768 million confirmed cases and 6.9 million deaths had been documented as of July 17, 2023. Coronaviruses have a relatively large RNA genome.
View Article and Find Full Text PDFMultifaceted interplays between the essential players and lipid peroxidation in ferroptosis.
J Genet Genomics
January 2025
Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China; Biomedical Sciences College & Shandong Medicinal Biotechnology Centre, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China. Electronic address:
Ferroptosis, a type of programmed cell death, represents a distinct paradigm in cell biology. It is characterized by the iron-dependent accumulation of reactive oxygen species, which induce lipid peroxidation (LPO), and is orchestrated by the interplay between iron, lipid peroxides, and glutathione. In this review, we emphasize the frequently overlooked role of iron in LPO beyond the classical iron-driven Fenton reaction in several crucial processes that regulate cellular iron homeostasis, including iron intake and export as well as ferritinophagy, and the emerging roles of endoplasmic reticulum-resident flavoprotein oxidoreductases, especially P450 oxidoreductases, in modulating LPO.
View Article and Find Full Text PDFSubstitution load revisited: a high proportion of deaths can be selective.
Genetics
January 2025
Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA.
Haldane's Dilemma refers to the concern that the need for many "selective deaths" to complete a substitution (i.e. selective sweep) creates a speed limit to adaptation.
View Article and Find Full Text PDFGender and educational trends in lifetime risk, age at onset, expectancy, and survival with cardiovascular disease in Finland, 1996-2020.
J Gerontol B Psychol Sci Soc Sci
January 2025
Helsinki Institute for Demography and Population Health, Faculty of Social Sciences, University of Helsinki, Helsinki, Finland.
Objectives: Cardiovascular disease (CVD) is the leading cause of mortality globally. Examining trends in CVD burden and associated sociodemographic disparities can contribute to tailoring policies that promote cardiovascular health and narrow health disparities. However, existing studies predominantly focus only on mortality.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!