Radioimmunoassay data on the determination of the plasma levels of free and bound forms of thyroid hormones and TSH in various types of primary hypothyrosis were analyzed. The variability of analyzed indices was revealed; changes in the thyroid status according to the results of hormonal investigations were more noticeable in idiopathic hypothyrosis, the least noticeable in patients with hypothyrosis operated on for diffuse toxic goiter. Changes detected in patients with severe-type hypothyrosis did not depend on the type of disease.

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