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Approaches to Incorporation of Preferences into Health Economic Models of Genomic Medicine: A Critical Interpretive Synthesis and Conceptual Framework.
Appl Health Econ Health Policy
January 2025
Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Introduction: Genomic medicine has features that make it preference sensitive and amenable to model-based health economic evaluation. Preferences of patients, caregivers, and clinicians related to the uptake and delivery of genomic medicine technologies and services that are not captured in health state utility weights can affect the intervention's cost-effectiveness and budget impact. However, there is currently no established or agreed-on approach for integrating preference information into economic evaluations.
View Article and Find Full Text PDFAdvances in waste-derived functional materials for PFAS remediation.
Biodegradation
January 2025
Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Negeri Jakarta, Rawamangun, Jakarta Timur, Indonesia.
Per- and polyfluoroalkyl substances (PFAS) are synthetic organofluoride compounds, widely used in industries since the 1950s for their hydrophobic properties. PFAS contamination of soil and water poses significant environmental and public health risks due to their persistence, chemical stability, and resistance to degradation. The Chemical Abstracts Service catalogs approximately 4300 PFAS globally.
View Article and Find Full Text PDFYAU renal cancer spotlight: how should cost-effectiveness affect decision-making regarding adjuvant pembrolizumab for clear cell renal cell carcinoma?
Minerva Urol Nephrol
December 2024
European Association of Urology (EAU), Young Academic Urologists (YAU) Renal Cancer Working Group, Arnhem, the Netherlands.
Multigas Identification by Temperature-Modulated Operation of a Single Anodic Aluminum Oxide Gas Sensor Platform and Deep Learning Algorithm.
ACS Sens
January 2025
Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea.
Semiconductor metal oxide (SMO) gas sensors are gaining prominence owing to their high sensitivity, rapid response, and cost-effectiveness. These sensors detect changes in resistance resulting from oxidation-reduction reactions with target gases, responding to a variety of gases simultaneously. However, their inherent limitations lie in selectivity.
View Article and Find Full Text PDFSprayable Hydrogel for pH-Responsive Nanozyme-Derived Bacteria-Infected Wound Healing.
ACS Appl Mater Interfaces
January 2025
School of Chemistry & Materials Science, Jiangsu Normal University, 101 Shanghai Road, Xuzhou 221116, P. R. China.
Long-term inflammation and persistent bacterial infection are primary contributors to unhealed chronic wounds. The use of conventional antibiotics often leads to bacteria drug resistance, diminishing wound healing effectiveness. Nanozymes have become a promising alternative to antimicrobial materials due to their low cost, easy synthesis, and good stability.
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