Biofilm removal efficacy of vortexing alone was compared with the standard vortexing-sonication procedure. Among 135 removed prostheses, 35 were diagnosed with infection and 100 with aseptic failure. At a cutoff of ≥ 50 CFU/ml, sonication was more sensitive than vortexing (60% versus 40%, P = 0.151), while the specificity was 99% for both methods.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553884PMC
http://dx.doi.org/10.1128/JCM.02482-12DOI Listing

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