AI Article Synopsis
- The study aimed to assess bone regeneration in defects around titanium implants coated with nanohydroxyapatite/bioactive glass (nHA/BG) in combination with Bio-Oss.
- Four Beagle dogs had premolars extracted, and defects were created around implants with different treatment groups, followed by a histomorphometric analysis.
- Results showed that while nHA/BG implants had better bone-integrated contact (BIC) at 8 and 16 weeks compared to mHA/Bio-Oss, the application of Bio-Oss did not hinder nHA/BG performance but helped stabilize newly formed bone.
Article Abstract
Purpose: To evaluate bone regeneration in defects at titanium implants with nHA/BG coating in conjunction with Bio-Oss.
Methods: Four mandibular premolars were extracted in 6 Beagle dogs. After 3 months, buccal dehiscence-type defects (2.25 mm×3 mm×4 mm) were surgically created following implant site. The three treatment modalities were randomly allocated: nHA/BG implant/Bio-Oss, nHA/BG implant/blood clot, and mHA implant/Bio-Oss. After 8 and 16 weeks, the dogs were sacrificed respectively. A histomorphometric analysis was performed. The data was analyzed with SPSS 13.0 software package for Student's t test and ANOVA.
Results: At 8- and 16-week, nHA/BG implant group revealed comparable mean BIC (30% to 18% versus 61% to 53%). However, mHA implant/Bio-Oss group revealed significantly lower mean BIC (21% versus 46%) values than nHA/BG implant/Bio-Oss group.A significant difference was observed for the mean BIC and RA values at 8-week between nHA/BG implant/Bio-Oss group and mHA implant/Bio-Oss group.
Conclusions: It is concluded that the application of Bio-Oss graft did not seem to interfere with the nHA/BG coating activity, but ensured a stabilization of the newly formed bone for defects.
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[Experimental study of osseointegration of nHA/BG coating and Bio-Oss in implant defects].
Shanghai Kou Qiang Yi Xue
August 2012
Department of Prosthodontics, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
Article Synopsis
- The study aimed to assess bone regeneration in defects around titanium implants coated with nanohydroxyapatite/bioactive glass (nHA/BG) in combination with Bio-Oss.
- Four Beagle dogs had premolars extracted, and defects were created around implants with different treatment groups, followed by a histomorphometric analysis.
- Results showed that while nHA/BG implants had better bone-integrated contact (BIC) at 8 and 16 weeks compared to mHA/Bio-Oss, the application of Bio-Oss did not hinder nHA/BG performance but helped stabilize newly formed bone.
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