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Comparison of computed tomography versus magnetic resonance imaging in assessing radiofrequency ablation margins after radiofrequency ablation in patients with hepatocellular carcinomas. | LitMetric

AI Article Synopsis

  • The study aimed to evaluate the effectiveness of MRI compared to CT in monitoring patients with hepatocellular carcinomas that were treated using radiofrequency ablation (RFA).
  • MRI showed significantly higher diagnostic accuracy and reliability compared to CT, as indicated by better sensitivity, specificity, and predictive values. The interobserver agreement rate for MRI was also notably higher.
  • Overall, the results concluded that MRI is a more effective imaging tool than CT for assessing RFA margins in patients with liver cancer.

Article Abstract

Objective: To assess the diagnostic value of magnetic resonance imaging (MRI) in the follow-up of patients with hepatocellular carcinomas treated with radiofrequency ablation (RFA) and to compare it with that of computed tomography (CT).

Methods: From December 2009 to September 2011, 40 patients (47 hepatocellular carcinomas) were treated with RFA after transcatheter arterial chemoembolization and underwent MRI and CT for follow-up. RFA margins were assessed on a five-point scale with receiver operating characteristic curve analysis. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were evaluated.

Results: The interobserver agreement rate for MRI was significantly higher (Kappa=0.935) than for CT (Kappa=0.714; P < 0.05). The scores of 1 and 5 points for MRI, which confirms the presence or absence of residual tumor, accounted for 89.4% (84/94), while for CT accounting for only 31.9% (30/94). The area under the receiver operating characteristic curve of MRI was significantly higher than that of CT (P < 0.05), as were the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of detection rate (mean, 100%, 96.4%, 76.9%, 100%, and 96.8% for MRI, respectively, vs. 30.0%, 57.1%, 10.3%, 87.7%, and 63.8% for CT).

Conclusion: MRI is superior to CT in assessing the RFA margins in terms of the diagnostic accuracy and detection rate .

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Source
http://dx.doi.org/10.3881/j.issn.1000-503X.2012.05.008DOI Listing

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