Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487817PMC
http://dx.doi.org/10.1186/1710-1492-8-s1-a1DOI Listing

Publication Analysis

Top Keywords

canadian society
4
society allergy
4
allergy clinical
4
clinical immunology
4
immunology annual
4
annual scientific
4
scientific meeting
4
meeting 2012
4
2012 calgary
4
calgary canada
4

Similar Publications

This study was designed to assess the effect of brentuximab vedotin on several breast cancer cell lines in terms of promoting apoptosis and managing cancer progression. Additionally, the study investigated the potential of repurposing this drug for new therapeutic reasons, beyond its original indications. The study evaluates the cytotoxic effects of Brentuximab vedotin across five cell lines: normal human skin fibroblasts (HSF), three breast cancer cell lines (MCF-7, MDA-MB-231, and T-47D), and histiocytic lymphoma (U-937).

View Article and Find Full Text PDF

Rhombencephalitis in an 86-year-old woman with chronic lymphocytic leukemia.

CMAJ

January 2025

Temerty Faculty of Medicine (Tilley, Kim, Lass), University of Toronto; Departments of Medicine (Silverstein) and Neurology (Masellis), Sunnybrook Health Sciences Centre, Toronto, Ont.

View Article and Find Full Text PDF

People with type 2 diabetes (T2D) have a greater risk of developing neurodegenerative diseases, like Alzheimer's disease, in later life. Exogenous ketone supplements containing the ketone body β-hydroxybutyrate (β-OHB) may be a strategy to protect the brain as β-OHB can support cerebral metabolism and promote neuronal plasticity via expression of brain-derived neurotrophic factor (BDNF). Parallel human (ClinicalTrials.

View Article and Find Full Text PDF

Allergic Reactivity and Memory Occur Independently of Sequential Switching Through IgG1.

Allergy

January 2025

Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Canada.

Allergic reactions to foods are primarily driven by allergen-binding immunoglobulin (Ig)E antibodies. IgE-expressing cells can be generated through direct switching from IgM to IgE or a sequential class switching pathway where activated B cells first switch to an intermediary isotype, most frequently IgG1, and then to IgE. It has been proposed that sequential class switch recombination is involved in augmenting the severity of allergic reactions, generating high affinity IgE, differentiation of IgE plasma cells, and in holding the memory of IgE responses.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!