AI Article Synopsis

  • Primary angiosarcoma is a rare and aggressive cancer originating from endothelial cells, often found in the skin and subcutaneous tissues.
  • When it appears in the intestine, it can be mistaken for primary colorectal cancer, complicating diagnosis.
  • A case study of a 59-year-old man revealed epithelioid angiosarcoma in the sigmoid colon, linked to a previous angiosarcoma in his thigh, with careful histopathology helping confirm the diagnosis.

Article Abstract

Primary angiosarcoma is an extremely rare and aggressive soft-tissue malignancy of endothelial cell origin that occurs most frequently in the skin and subcutaneous tissues of the extremities. Presence of this disease in the intestine as a primary or metastatic deposit is an extremely uncommon incident, and might causes diagnostic confusion with primary colonic neoplasm. We encountered epithelioid angiosarcoma of the sigmoid colon in a 59-year-old male patient who presented with occasional bleeding per rectum and had also had an angiosarcoma arising from the subcutaneous tissue of the right thigh. Retrospective review of histopathology and immunohistochemistry of the two specimens were helpful in the final diagnosis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3451850PMC
http://dx.doi.org/10.1007/s12262-010-0089-1DOI Listing

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