Background: Urticaria is a common dermatological manifestation in adults with relatively infrequent occurrence of chronic urticaria (CU) in childhood. The etiology of urticaria in childhood remains incompletely understood because of limited data on children.
Objective: We carried out this retrospective data-based study to determine different etiological factors and response to treatment in pediatric patients presenting with urticaria.
Materials And Methods: EIGHTY CHILDREN (M : F 49 : 31) between the ages of 1 and 14 years, who presented with urticaria excluding patients of physical urticaria attending the Outpatient Department of Pediatrics and Dermatology were included in the study. Patients were evaluated after taking a detailed history, doing a thorough physical examination, and basic laboratory investigations. Specific in vivo and in vitro tests were performed after the initial evaluation and consent of patients.
Results: Out of eighty patients, 35 (43.75%) presented with acute urticaria and 45 (56.25%) gave a history of chronic urticaria.CU. An underlying cause was suspected in 53 cases (66.25%), although a definite association with response to a specific treatment was correlated in 30 (37.5%). Infection was the most common underlying causative factor. Underlying thyroid dysfunction was observed in 12 patients, of whom two had thyroid anti peroxidase antibodies. Autologous serum skin test was positive in 17 patients.
Conclusions: In the present study infections were the most common etiological factor for urticaria in children.
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http://dx.doi.org/10.4103/2229-5178.85992 | DOI Listing |
Sports Med
January 2025
Department of Sport Science and Physical Education, Faculty of Health and Sport Sciences, University of Agder, Kristiansand, Norway.
Background: Endurance athletes tend to accumulate large training volumes, the majority of which are performed at a low intensity and a smaller portion at moderate and high intensity. However, different training intensity distributions (TID) are employed to maximize physiological and performance adaptations.
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Brain Imaging Behav
January 2025
Faculty of Economics and Business, University of Granada, Campus Universitario de Cartuja, Granada, CP, 18071, Spain.
Detecting the factors associated with financial decision-making is an unresolved challenge when trying to predict digital financial behavior. This paper reports experimental results on both neuropsychological and neuronal correlates of risk-taking and betrayal aversion among 121 healthy participants (X=21.7; SD = 2.
View Article and Find Full Text PDFInt J Biometeorol
January 2025
Division of International Health Public Health, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi dori, Chuo-ku, Niigata City, Niigata, 951-8510, Japan.
Varicella, commonly referred to as chickenpox, is an airborne infectious disease that continues to pose an increasing threat to public health. Despite previous investigations, the global accumulation of epidemiological studies exploring the association between varicella epidemics and meteorological factors remains insufficient. This study aimed to quantify the short-term effect of meteorological factors, such as mean temperature and relative humidity, on the incidence of varicella across all 47 prefectures of Japan over a decade (2010-2019).
View Article and Find Full Text PDFPsychopharmacology (Berl)
January 2025
Hotchkiss Brain Institute, Alberta Children's Hospital Research Institute, Mathison Centre for Mental Health Research and Education, University of Calgary, Calgary, AB, Canada.
Rationale: Current treatment options for PTSD have unreliable efficacy, with many individuals unable to achieve complete remission. Cannabis and cannabinoids that act through the endogenous cannabinoid (endocannabinoid) system to help promote trauma recovery by means of enhanced extinction learning are potential therapeutic, pharmacological candidates. Using a preclinical model of translationally-relevant cannabis administration in rodents, we examined the impact of cannabis exposure on aversive memory.
View Article and Find Full Text PDFBr J Dermatol
January 2025
Inflammatory Immune-Mediated Chronic Skin Diseases Laboratory (GC26), Maimonides Biomedical Research Institute of Cordoba (IMIBIC)/University of Cordoba/Reina Sofia University Hospital, Menendez Pidal Ave, 14004, Córdoba, Spain.
Introduction: Non-segmental vitiligo (NSV) is an autoimmune condition characterized by melanocyte loss. While skin-specific mechanisms are well-studied, systemic immune dysregulation contributing to NSV pathogenesis remains unclear.
Objective: This study employs a multi-omic single-cell approach to investigate circulating immune cells in NSV, integrating transcriptional and chromatin accessibility data.
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