The present study was performed in China to compare the efficacy and safety of an advanced wound dressing made of crystalline cellulose (Veloderm) to a conventional treatment of three Vaseline gauzes in the management of skin donor sites of burns or reconstructive plastic surgery. In this prospective, multicenter, open-labeled, randomized clinical trial performed in three Chinese burn centers in China, 96 patients who required autologous split skin graft were randomized into either the test (Veloderm) group or the control (Vaseline gauze) group. Average healing times in the test group and in the control group were 8.40±2.90 and 8.92±2.58 days, respectively, with median values of 7.00 and 8.00 days, respectively: the difference between two groups was statistically significant (P=.045). Scores for exudates, pain intensity, and peripheral erythema showed no difference between the groups; however, composite scores of three variables on day 10 postoperatively was significantly lower in the test group (0.00±0.00 vs. 0.13±0.49; P = .043). The need for a dressing change was also significantly lower in the test group (12.5 vs. 31.25%; P = .036). Veloderm is a safe and effective dressing that may offer some advantages over the traditional application of Vaseline gauze in the management of donor sites in burn or reconstructive plastic surgery patients.
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http://dx.doi.org/10.1097/BCR.0b013e31825d5d8d | DOI Listing |
Adv Biotechnol (Singap)
June 2024
MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, Guangdong, 510275, China.
Autosomal dominant polycystic kidney disease (ADPKD) is a dominant genetic disorder caused primarily by mutations in the PKD1 gene, resulting in the formation of numerous cysts and eventually kidney failure. However, there are currently no gene therapy studies aimed at correcting PKD1 gene mutations. In this study, we identified two mutation sites associated with ADPKD, c.
View Article and Find Full Text PDFAnn Chir Plast Esthet
January 2025
Service ORL et chirurgie cervico-faciale, centre hôpital universitaire Lariboisière, AP-HP, 2, rue Ambroise-Paré, 75010 Paris, France. Electronic address:
Total nasal reconstruction represents a complex challenge, requiring restoration of all three anatomical planes while preserving respiratory function. This procedure has significant therapeutic, aesthetic, social and professional implications for patients. We share our academic experience of reconstruction using a folded microanastomosed radial forearm flap (FRFF) combined with a paramedian forehead flap, using the technique of F.
View Article and Find Full Text PDFEnviron Sci Technol
January 2025
State Key Laboratory of Green Chemical Engineering and Industrial Catalysis, Research Institute of Industrial Catalysis, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, PR China.
Catalytic elimination through an oxidative decomposition pathway is the most promising candidate for the purification of chlorinated volatile organic compound (CVOC) pollutants, but the complicated mechanisms and the formation pathways of hydrogenated byproducts still need to be clearly revealed. Herein, W/ZrO, as a structure-tunable catalyst, is used to catalytically oxidize dichloromethane (DCM) and clarify the formation pathway of monochloromethane (MCM). Crystal engineering of ZrO tailors surface WO species; practically, the predominant Zr-WO clusters and crystalline WO can be obtained on monoclinic (m-ZrO) and tetragonal (t-ZrO) phases.
View Article and Find Full Text PDFCornea
January 2025
Tissue Engineering & Cell Therapy Group, Singapore Eye Research Institute, Singapore.
Purpose: Conjunctival autografts (CAGs) are the gold standard treatment after pterygium resection, but it is challenging to achieve consistently thin Tenon-free CAGs with manual dissection. We herein report the reproducibility and clinical outcomes of a novel algorithm to produce customizable trapezoidal CAGs using femtosecond laser (femtosecond lasers)-assisted pterygium surgery.
Methods: We first tested this algorithm in 4 pig eyes to show reproducibility.
Med Klin Intensivmed Notfmed
January 2025
Klinik für vaskuläre Neurologie und Klinik für Neuroonkologie, Zentrum für Neurologie, Universitätsklinikum Bonn, Bonn, Deutschland.
Background: The persistently low number of postmortem organ donations in Germany has repeatedly led to political discussions and most recently to the amendment of the Transplantation Act with the strengthening of the role of the transplantation officer and the introduction of a register to document the will to donate. The background to these decisions was the assumption that a relevant proportion of potential organ donors in hospitals were being overlooked and not reported. However, due to the lack of guidelines as to when a potential organ donor must be reported to the DSO ("Deutsche Stiftung Organspende"), the existing data is only of limited validity.
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