Contemporary theoretical models that conceptualize attachment as a biologically-based behavioral system that is activated under threat offer a heuristic theoretical framework to understand processes involved in aging and particularly individual differences in coping with the inevitable losses associated with aging and age-related disease, including dementia. This paper provides a systematic qualitative review of research concerning attachment in old age published between 1983 and June 2012. Four major findings emerged. First, studies suggest age-related changes with regard to the number and type of attachment figures, with older adults, compared to younger adults, having less attachment relations. Moreover, so-called symbolic attachments (e.g., to God or a deceased loved one) become more prominent in old age. Second, the quality of attachment changes with increasing age, with significant decreases in attachment anxiety, but not in attachment avoidance. Third, late-life attachment is in theoretically predicted ways associated with indices of intraindividual and interindividual functioning. Finally, insecure attachment has a negative impact on subjective caregiver burden and behavior of patients with dementia. There is some evidence suggesting that attachment-based interventions show positive effects in treating problem behaviors associated with dementia. However, these conclusions need to be interpreted within the context of important methodological limitations, stressing the need for future research in this domain. Guidelines for future research are outlined.
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http://dx.doi.org/10.1016/j.cpr.2012.10.003 | DOI Listing |
Front Immunol
January 2025
Department of Preventive Medicine, Shantou University Medical College, Shantou, China.
Background: Colon adenocarcinoma (COAD) is a malignancy with a high mortality rate and complex biological characteristics and heterogeneity, which poses challenges for clinical treatment. Anoikis is a type of programmed cell death that occurs when cells lose their attachment to the extracellular matrix (ECM), and it plays a crucial role in tumor metastasis. However, the specific biological link between anoikis and COAD, as well as its mechanisms in tumor progression, remains unclear, making it a potential new direction for therapeutic strategy research.
View Article and Find Full Text PDFFor long-lived species with biparental care, coordination and compatibility in the foraging behavior of breeding mates may be crucial to successfully raise offspring. While high foraging success is clearly important to reproductive success, it might be equally important that the mate has a complementary foraging strategy. We test whether breeding partners have similar or dissimilar foraging strategies in a species where both partners share breeding responsibilities and exhibit high mate fidelity (thick-billed murre; ).
View Article and Find Full Text PDFFront Surg
January 2025
Service de Chirurgie Orthopédique et Traumatologique, Cliniques Universitaires Saint-Luc, Bruxelles, Belgique.
Background: Rotationplasty, an invasive surgery, serves as an alternative to amputation in pediatric orthopedic oncology. It is currently applied in broader cases (e.g.
View Article and Find Full Text PDFHeliyon
January 2025
Department of Chemical Engineering, Quchan Branch, Islamic Azad University, Quchan, Iran.
An interface can be delicately designed using interactions between nanoparticles and surfactants by controlling surface properties such as activity and charge equilibrium. This study seeks to provide insights into how surfactant concentration impacts the stability and dynamics of nanoparticle-surfactant interfaces, with potential applications in material science and interface engineering. This study investigates the interactions between Graphene Function (Gr, Graphene function in this text refers to functionalizing the graphene sheets with -COOH groups via acidic reactions.
View Article and Find Full Text PDFTzu Chi Med J
September 2024
School of Medicine, Tzu Chi University, Hualien, Taiwan.
Objectives: Gastric cancer (GC) is one of the most malignant tumors. Mounting studies highlighted gastric cancer stem cells (GCSCs) were responsible for the failure of treatment due to recurrence and drug resistance of advanced GC. However, targeted therapy against GCSC for improving GC prognosis suffered from lack of suitable models and molecular targets in terms of personalized medicine.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!