Introduction: Caries lesions in dental hard tissues autofluoresce when exposed to light of certain wavelengths, whereas sound tissues do not, and this can be used as an in vitro histological marker for dental caries. Detection of autofluorescence is the basis of KaVo DIAGNOdent™ technology, and provides objective feedback control of laser-stimulated ablation of dental caries for the KaVo Key Laser 3™. This Er:YAG laser operates at 2940nm wavelength, and is effective at removal of infected dental hard tissues. Micro-computed tomography (micro-CT) allows the non-invasive investigation of three-dimensional structures and analysis of mineral density profiles of dentine following laser ablation.
Objective: To evaluate removal of infected, demineralised dentine by Er:YAG irradiation with a laser feedback mechanism, using micro-CT.
Design: 27 carious teeth (1 control) and 1 sound tooth, treated with the KaVo Key Laser 3™ using a KaVo™ non-contact 2060 handpiece at specific feedback settings, were examined using a Skyscan 1172 Micro-CT, to observe the efficiency of demineralised dentine removal. Grey scale images obtained were colour rendered to assist detection of demineralised tissue if present.
Results: Complete removal of demineralised tissue occurred with laser-stimulated ablation under feedback control at values of 7 and 8 when measured by micro-CT. At greater values, removal of demineralised dentine was incomplete.
Conclusion: Examination of dental tissues by micro-CT allowed determination of the efficiency of Er:YAG laser-stimulated ablation. Feedback control of the KaVo Key Laser 3™ appeared to operate like a cut-off switch when infected dentine was eliminated, at a threshold of between 6 and 7.
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http://dx.doi.org/10.1016/j.archoralbio.2012.09.017 | DOI Listing |
JAC Antimicrob Resist
February 2025
Inserm, INSPIIRE, Université de Lorraine, Nancy F-54000, France.
Background: Antibiotic resistance in nursing homes (NHs) is inconsistently tackled by antimicrobial stewardship programmes. The literature on individual determinants of antibiotic prescriptions (APs) in NHs is extensive. However, less is known about the structural determinants of AP in NHs.
View Article and Find Full Text PDFBMC Res Notes
January 2025
Nurses International, PO Box 114, Anoka, MN, 55303, USA.
Background: The recent global pandemic posed extraordinary challenges for healthcare systems. Frontline healthcare workers required focused, immediate, practical, evidence-based instruction on optimal patient care modalities as knowledge evolved around disease management.
Objective: This course was designed to provide knowledge to protect healthcare workers; combat disease spread; and improve patient outcomes.
BMC Public Health
January 2025
National Institute for Health Research (NIHR) School for Public Health Research (SPHR), Newcastle, UK.
Background: In England, 23% of children aged 11 start their teenage years living with obesity. An adolescent living with obesity is five times more likely to live with obesity in adult life. There is limited research and policy incorporating adolescents' views on how they experience the commercial determinants of dietary behaviour and obesity, which misses an opportunity to improve services and policies that aim to influence the prevalence of childhood obesity.
View Article and Find Full Text PDFACS Nano
January 2025
Department of Physics and Astronomy, University of Manitoba, Winnipeg R3T 2N2, Canada.
Theory and simulations are used to demonstrate implementation of a variational Bayes algorithm called "active inference" in interacting arrays of nanomagnetic elements. The algorithm requires stochastic elements, and a simplified model based on a magnetic artificial spin ice geometry is used to illustrate how nanomagnets can generate the required random dynamics. Examples of tracking and PID control are demonstrated and shown to be consistent with the original stochastic differential equation formulation of active inference.
View Article and Find Full Text PDFPsychooncology
January 2025
Cancer Prevention Precision Control Institute, Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.
Background: Although scanxiety is common and impactful for people with advanced lung cancer, few interventions address this psychosocial concern.
Aims: To create a stress management program for scanxiety.
Methods: We conducted a structured intervention adaptation process guided by the ADAPT-ITT framework.
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