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http://dx.doi.org/10.1016/j.nedt.2012.10.003 | DOI Listing |
Comput Biol Med
January 2025
Department of Management and Engineering, University of Padova, Stradella San Nicola 3, 36100, Vicenza, Italy. Electronic address:
Digital workflows have revolutionized dentistry, especially when it comes to fabrication of complete dentures through Computer-Aided Design and Computer-Aided Manufacturing (CAD-CAM) procedures. Digital articulators manage to simulate mandibular movements and are emerging as alternatives to mechanical articulators like the Gerber semi-adjustable model. Despite being a promising tool, digital articulators require refinement in order to grant consistent functionality and effective occlusal balance.
View Article and Find Full Text PDFSci Rep
January 2025
Dipartimento di Scienze Biologiche, Geologiche ed Ambientali, Università di Bologna, Bologna, Italy.
Heterogeneous fault architecture affects crustal seismotectonics and fluid migration. When studying it, we commonly rely on static conceptual models that generally overlook the absolute time dimension of fault (re)activation. Heterogenous faults, however, represent the end-result of protracted, cumulative and intricate deformation histories.
View Article and Find Full Text PDFSci Adv
January 2025
Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano and IU.NET, Piazza Leonardo da Vinci 32, 20133 Milano, Italy.
Neurological disorders are a substantial global health burden, affecting millions of people worldwide. A key challenge in developing effective treatments and preventive measures is the realization of low-power wearable systems with early detection capabilities. Traditional strategies rely on machine learning algorithms, but their computational demands often exceed what miniaturized systems can provide.
View Article and Find Full Text PDFNaturwissenschaften
January 2025
Programa de Pós-Graduação em Biodiversidade Animal, Universidade Federal de Santa Maria, Av. Roraima 1000, 97105-900, Santa Maria, RS, Brazil.
This paper analyzes the paleoneurology (cranial endocast and maxillary canal) of Massetognathus pascuali, an iconic non-mammaliaform cynodont from the early Late Triassic of South America, using Neutron Tomography. The application of neutron tomography holds the potential for uncovering more refined anatomical and quantitative data. The newly examined cranial endocast shows a forebrain with a tubular shape without an interhemispheric fissure, presence of a pineal body (with a closed parietal foramen), and a marked unossified zone.
View Article and Find Full Text PDFJ Prev Alzheimers Dis
January 2025
Clinical Memory Research Unit, Clinical Sciences in Malmö, Lund University, Lund, Sweden; Memory Clinic, Skåne University Hospital, Sweden. Electronic address:
As novel, anti-amyloid therapies have become more widely available, access to timely and accurate diagnosis has become integral to ensuring optimal treatment of patients with early-stage Alzheimer's disease (AD). Plasma biomarkers are a promising tool for identifying AD pathology; however, several technical and clinical factors need to be considered prior to their implementation in routine clinical use. Given the rapid pace of advancements in the field and the wide array of available biomarkers and tests, this review aims to summarize these considerations, evaluate available platforms, and discuss the steps needed to bring plasma biomarker testing to the clinic.
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