Enormous progress has been made in identifying chromatin "signatures" that define tissue-specific transcriptional networks. Three recent studies by Rada-Iglesias et al. (2012), Wamstad et al. (2012), and Paige et al. (2012) track such signatures during cellular differentiation, revealing a richer understanding of gene regulation and providing hints of new phenomena.
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http://dx.doi.org/10.1016/j.stem.2012.10.009 | DOI Listing |
Front Neurol
January 2025
Department of Kinesiology, Penn State University, 19 Recreation Building, University Park, PA, United States.
Introduction: Resting state-fMRI, provides a sensitive method for detecting changes in brain functional integrity, both with respect to regional oxygenated blood flow and whole network connectivity. The primary goal of this report was to examine alterations in functional connectivity in collegiate American football players after a season of repetitive head impact exposure.
Methods: Collegiate football players completed a rs-fMRI at pre-season and 1 week into post-season.
Cartilage
January 2025
High-Field MR Centre, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Objective: The objective of this study was to assess the maturation of matrix-associated autologous chondrocyte transplantation (MACT) grafts up to 2 years after the surgery using gray-level co-occurrence matrix (GLCM) texture analysis of quantitative T maps, compare the results with the microfracturing technique (MFX) control group, and relate these results to the morphological MOCART 2.0 score.
Design: A subcohort of 37 patients from prospective, multi-center study underwent examination on a 3T MR scanner, including a T mapping sequence at 3, 12, and 24 months after surgery.
Radiat Oncol
January 2025
German Cancer Consortium (DKTK), partner site Tübingen, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Background: For radiotherapy of head and neck cancer (HNC) magnetic resonance imaging (MRI) plays a pivotal role due to its high soft tissue contrast. Moreover, it offers the potential to acquire functional information through diffusion weighted imaging (DWI) with the potential to personalize treatment. The aim of this study was to acquire repetitive DWI during the course of online adaptive radiotherapy on an 1.
View Article and Find Full Text PDFNat Commun
January 2025
School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul, Republic of Korea.
Colloidal nanocrystals inherently undergo structural changes during chemical reactions. The robust structure-property relationships, originating from their nanoscale dimensions, underscore the significance of comprehending the dynamic structural behavior of nanocrystals in reactive chemical media. Moreover, the complexity and heterogeneity inherent in their atomic structures require tracking of structural transitions in individual nanocrystals at three-dimensional (3D) atomic resolution.
View Article and Find Full Text PDFIntegr Environ Assess Manag
January 2025
Faculty of Fine Arts, Design and Architecture Department of Landscape Architecture, Tekirdağ Namık Kemal University, Tekirdağ, Türkiye.
Wetlands provide necessary ecosystem services, such as climate regulation and contribution to biodiversity at global and local scales, and they face spatial changes due to natural and anthropogenic factors. The degradation of the characteristic structure signals potential severe threats to biodiversity. This study aimed to monitor the long-term spatial changes of the Göksu Delta, a critical Ramsar site, using remote sensing techniques.
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