Porokeratosis of Mibelli is an uncommon dermatosis, which may be associated with immunosuppression and which may undergo malignant transformation. We report a patient with a chronic history of a skin lesion of his right 5th finger that was histologically confirmed to be Porokeratosis of Mibelli. Although it commonly affects the extremities, the isolated involvement of an individual digit of the hand has not been previously reported.
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J Cutan Med Surg
January 2025
Department of Dermatology, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Indian Dermatol Online J
July 2024
Consultant Dermatologist, Dermatology, Bharti Derma Care and Research Centre, Amritsar, Punjab, India.
Follicular porokeratosis (FPK) is a rare subtype of porokeratosis. Follicular porokeratosis mainly occurs in men and may be localized or diffuse. Involvement of the scalp is rarely reported, and we found only one case of alopecia due to scalp FPK.
View Article and Find Full Text PDFSAGE Open Med Case Rep
January 2025
Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Porokeratosis is a condition characterized by abnormal epidermal keratinization with a unique morphology of papules or plaques surrounded by a thread-like border of scale corresponding to the cornoid lamella on histology. Many established subtypes have been described; however, genitogluteal porokeratosis is a rare entity. We present the case of a 58-year-old male with pruritic reddish lesions affecting the genitals and thighs, diagnosed with genital porokeratosis.
View Article and Find Full Text PDFJ Cutan Pathol
January 2025
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
The term autoinflammatory keratinization diseases (AIKDs) was recently proposed as a unifying concept for diseases characterized by inflammation in the epidermis and upper dermis which leads to hyperkeratosis, caused by genetic perturbations of the innate immune system. We present a case of a patient with hidradenitis suppurativa and porokeratosis, two AIKDs, followed by a review of these conditions as well as other AIKDs. This case was distinguished by hypertrophic porokeratoses involving cystic hair follicles, showing histopathologic features of both conditions within single biopsy specimens.
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