AI Article Synopsis
- A new thiophene building block has been synthesized, featuring both a stannyl group and a boronic ester.
- A novel one-pot reaction was created that selectively reacts with nucleophiles, taking advantage of the different behaviors in Stille and Suzuki-Miyaura cross-coupling methods.
- Various aromatic electrophiles were tested, showcasing the broad tolerance for different functional groups in this reaction.
Article Abstract
A new thiophene building block, containing both a stannyl group and a boronic ester, was prepared. From this starting material, a general, nucleophile-selective one-pot reaction was developed, exploiting the different reactivities of the Stille and Suzuki-Miyaura cross-coupling reactions. A series of aromatic electrophiles were used to demonstrate the high functional group tolerance.
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| http://dx.doi.org/10.1021/ol302571t | DOI Listing |
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