Objective: To characterize the clinical behavior of rare sinonasal malignancies.
Methods: Clinical data from the cases of rare sinonasal malignancies at Gujarat Cancer and Research Institute during 2001-2007 were extracted. Data for histologic type of tumor, tumor stage and survival were analyzed.
Results: Eighty-nine cases of the non-squamous cell malignancy were identified. The mean patient age was 54 years. In this study, we found minor salivary gland tumor in 31 patients, sarcoma in 19 patients, spindle cell carcinoma (SpCC) in 19 patients, undifferentiated carcinoma in 9 patients, lymphoma in 6 patients and melanoma in 3 patients. Adenoid cystic carcinoma exhibited the best survival rate (3 years survival rate was 77%), whereas melanoma and undifferentiated carcinoma exhibited poor survivals (1 year survival was 25% and 33%, respectively and 3 years survival rate is 0%).
Conclusions: Adenoid cystic carcinoma is the most common squamous cell carcinoma (SCC) of the sinonasal track. Survival for the patients with undifferentiated carcinoma and melanoma involving the sinonasal track is poor.
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http://dx.doi.org/10.1007/s12070-010-0038-0 | DOI Listing |
Otolaryngol Head Neck Surg
December 2024
Department of Otolaryngology-Head and Neck Surgery, National Taiwan University Hospital and Children's Hospital, Taipei, Taiwan.
Objective: To present workplace-based entrustable professional activities (EPAs) assessment data from the first 2 years of the EMYWAY platform in otolaryngology residency training in Taiwan.
Study Design: Two-year cross-sectional study.
Setting: Otolaryngology training programs.
Neuroradiology
December 2024
Department of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1 of Dongjiaominxiang Street, Dongcheng District, Beijing, 100730, China.
Purpose: The purpose of this study was to evaluate the additional value of dynamic contrast-enhanced (DCE) MRI and diffusion weighted MRI (DWI) in differentiation between inflammatory myofibroblastic tumor (IMT) and squamous cell carcinoma (SCC) in the sinonasal cavity.
Methods: Patients with pathologically proven IMT and SCC in the sinonasal region were enrolled in this retrospective study. All participants underwent conventional MRI and dynamic contrast-enhanced MRI, while a subset of them performed DWI.
Acta Otolaryngol
December 2024
Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Denmark.
Background: Inverted papilloma is a benign epithelial tumour located in the sinonasal tract with a high recurrence rate and a potential of malignant transformation. From 2017, patients with IP were included in our fast-track regime similar to head and neck cancer patients, including follow-up at 2, 6, 12, 18 and 24 months after surgery, then yearly for a total of 5 years.
Aims/objectives: This study aims to compare the recurrence rate and malignant transformation of patients with IP treated at a university centre following the implementation of a fast-track regime including a close follow-up.
Clin Otolaryngol
July 2024
Department of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Objectives: Existing knowledge on health-related quality of life (HRQoL) after surgical removal of sinonasal inverted papilloma (IP) is limited. Moreover, predictors for a better or worse post-operative HRQoL outcome are not known. Our aim was to assess HRQoL in all three health domains (physical, psychological, and social), track its post-operative trajectory, investigate if pre-operative observations could predict distinct post-operative HRQoL outcomes, and evaluate whether physicians' interventions could contribute to improved post-operative HRQoL.
View Article and Find Full Text PDFInt J Pediatr Otorhinolaryngol
April 2024
Department of Otolaryngology-Head and Neck Surgery, Columbia University Vagelos College of Physicians and Surgeons, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA. Electronic address:
Background And Purpose: Olfactory dysfunction (OD) commonly occurs in patients with sinonasal dysfunction, but the prevalence and severity of olfactory issues in adolescents with cystic fibrosis (AwCF) is unclear. OD may contribute to dietary deficiencies and exacerbate nutritional challenges. We sought to review literature on the effectiveness of medical and surgical management of sinonasal symptoms in AwCF and the associated impact on olfactory function.
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