A series of high-resolution crystal structures of RIG-I and RIG-I:dsRNA cocrystals has recently been reported. Comparison of these structures provides considerable insight into how this innate immune pattern recognition receptor is activated upon detecting and binding a certain class of viral RNAs.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504664 | PMC |
| http://dx.doi.org/10.1261/rna.035949.112 | DOI Listing |
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