AI Article Synopsis

  • The study investigates the relationship between grapheme-color synesthesia, a phenomenon where letters or numbers trigger color perception, and posttraumatic stress disorder (PTSD) in US veterans, with a focus on neuropsychological functions.
  • Out of 700 surveyed veterans, it was found that 7% had current PTSD, 11% had partial PTSD, and 6% showed signs of grapheme-color synesthesia, with the latter being linked to higher odds of current PTSD.
  • The results suggest grapheme-color synesthesia may serve as a potential indicator for PTSD, highlighting the need for further research into its implications for diagnosis and treatment in both veterans and nonveterans.

Article Abstract

Objective: Posttraumatic stress disorder (PTSD) is associated with altered neuropsychological function, possibly including complex visual information processing. Grapheme-color synesthesia refers to the phenomenon that a particular letter or number elicits the visual perception of a specific color. The study objective was to assess if grapheme-color synesthesia was associated with PTSD among US veterans.

Method: We surveyed 700 veterans who were outpatients in a multihospital system in Pennsylvania. All veterans had served at least one warzone deployment. PTSD and grapheme-color synesthesia were assessed using validated research instruments.

Results: The mean age of veterans was 59 years, and 96% were men. The prevalence of current PTSD was 7% (95% confidence interval [CI] = 5.1-8.8), and current partial PTSD was 11% (95% CI = 9.3-14.0). The prevalence of current depression was 6% (95% CI = 4.7-8.3). Altogether, 6% (95% CI = 4.8-8.5) of veterans screened positive for grapheme-color synesthesia. Bivariate analyses suggested that grapheme-color synesthesia was associated with current PTSD (odds ratio [OR] = 3.4, p = .004) and current partial PTSD (OR = 2.4, p = .013), but not current depression (OR = 1.1, p = .91). Multivariate logistic regression results, adjusting for age, sex, marital status, level of education, current psychotropic medication use, and concussion history, confirmed these results.

Conclusions: Grapheme-color synesthesia seems to be associated with PTSD among veterans who had been deployed. This finding may have implications for PTSD diagnostic screening and treatment. Research is recommended to confirm this finding and to determine if synesthesia is a risk indicator for PTSD among nonveterans.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556719PMC
http://dx.doi.org/10.1097/PSY.0b013e3182731007DOI Listing

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