Basosquamous carcinoma (BSC) is a rare aggressive epithelial neoplasm with features of both basal cell carcinoma and squamous cell carcinoma, with a tendency toward local recurrence and a propensity for lymph node and distant metastases. The aim of the present study was to report the case of a 63-year-old Caucasian male with BSC in the auricular region.
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http://dx.doi.org/10.4103/0019-5154.100489 | DOI Listing |
Case Rep Oncol
November 2024
Faculty of Medicine of Tunis, University of Tunis Manar, Tunis, Tunisia.
J Cutan Pathol
February 2025
Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.
Background: Xeroderma pigmentosum (XP) is a genodermatosis, characterized both by premature aging and significantly increased risk of non-melanoma and melanoma skin cancers at an early age. However, limited literature is available on the common histopathological subtypes of basal cell carcinoma (BCC) in these patients.
Methods: In this ambispective case series, we recruited patients of XP who had either a currently present skin tumor or previously excised one, provided their histopathological sections were available.
Cureus
October 2024
Multidisciplinary Integrated Center of Dermatological Interface Research (MIC-DIR), "Dunărea de Jos" University, Galati, ROU.
Background: This study aims to explore the tumor-stroma separation or the cleft characterizing basal cell carcinoma (BCC).
Methodology: In this retrospective cohort investigation, we enrolled 244 patients who received a confirmed diagnosis of BCC through histopathological examination in the period of 2019-2020 at the Pathology Laboratory of the "Sfântul Apostol Andrei" Emergency Clinical Hospital located in Galați, Romania. The identification of patients was accomplished by utilizing electronic health records, and relevant clinical, demographic, and histopathological data were retrieved from the physical database of the Pathology Laboratory.
Appl Immunohistochem Mol Morphol
October 2024
Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing.
Background: Basaloid skin tumors include subtypes of basal cell carcinoma (BCC) and the basaloid variant of squamous cell carcinoma (SCC). Due to their similarity in pathology and clinical presentation, their diagnosis is not straightforward. The aim of this study was to analyze the immunohistochemical expression of HSP105 in basaloid skin tumors, which include BCC, basosquamous carcinoma (BSC), metatypical basal cell carcinoma (MBCC), basaloid squamous cell carcinoma (BSCC), BCC with squamous differentiation as well as conventional SCC.
View Article and Find Full Text PDFArch Dermatol Res
October 2024
Department of Dermatology, University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Several studies have been published describing development of cutaneous malignancy after vismodegib therapy; no systematic review has been conducted to interpret these data. Our objective was to systemically review reported cases of same-site or different-site cutaneous malignancy after smoothened inhibitor (SMOi) therapy for primary basal cell carcinoma (BCC). PubMed, CINAHL, and Scopus were systematically searched January 1, 2012 - March 28, 2024.
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