The term "inflammatory myofibrohistiocytic proliferation" (IMP) has been proposed to replace the conventional designations of plasma cell granuloma and inflammatory pseudotumor. Three cases of extrapulmonary IMP in children are reported, including an intracerebral lesion which has been formerly undescribed. In children, IMP may be associated with microcytic hypochromic anemia, hypergammaglobulinemia, and high erythrocyte sedimentation rate. In this clinical setting, differentiation of a rapidly growing but benign IMP from a bona fide sarcoma is of paramount importance.
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http://dx.doi.org/10.1002/1097-0142(19900401)65:7<1626::aid-cncr2820650729>3.0.co;2-v | DOI Listing |
Indian J Thorac Cardiovasc Surg
March 2024
Department of Pathology, Core Diagnostics, Gurgaon, Haryana India.
Follicular dendritic cell sarcoma (FDCS) is a rare, mesenchymal neoplasm that may be nodal or extranodal in location. Lung involvement is rare. It is a slow-growing, painless tumor with a frequent capacity to recur and metastasize.
View Article and Find Full Text PDFBladder (San Franc)
December 2019
Department of Pathology, RWJBarnabas Health, Livingston, NJ, USA.
Inflammatory myofibroblastic tumor (IMT) previously known as inflammatory pseudotumor, plasma cell granuloma, pseudosarcoma, myxoid hamartoma or inflammatory myofibrohistiocytic proliferation is recently recognized by World Health Organization (WHO) as "IMT" and is considered as a rare benign tumor of soft tissues occurring commonly in lung, liver and mesentry and omentum. IMT is mainly identified as a lesion of children and young population. In this report, we describe a rare case of IMT occurring in a 93-year-old female in urinary bladder with initial benign presentation but demonstrating rapid malignant transformation as confirmed with morphology and immunohistochemical (IHC) stains.
View Article and Find Full Text PDFTurk J Urol
December 2013
Department of Pathology, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize, Turkey.
Inflammatory pseudotumors (IPTs) are rare benign tumor-like lesions in the epididymis. They result from myofibrohistiocytic proliferation of the parenchymal organs of the body, such as the lungs and genitourinary system. A 48-year-old male patient presented with a palpable left scrotal mass and developed painless swelling within two months.
View Article and Find Full Text PDFJ Cancer Res Ther
December 2012
Department of Pathology, G B Pant Hospital, Jawaharlal Nehru Marg, New Delhi, India.
Inflammatory myofibroblastic tumor (IMT) has been described as a pseudosarcomatous proliferation of spindled myofibroblasts admixed with lymphoplasmacytic cells. The various terminologies like inflammatory pseudotumor, plasma cell granuloma, and inflammatory myofibrohistiocytic proliferation, used to describe this entity, highlight the controversial etiopathogenesis of this relatively indolent neoplasm. IMT has now been described in different anatomic locations.
View Article and Find Full Text PDFContemp Clin Dent
October 2011
Department of Oral Pathology, Sinhgad Dental College and Hospital, Pune, Maharashtra, India.
Inflammatory myofibroblastic tumor is an uncommon lesion of unknown cause. It encompasses a spectrum of myofibroblastic proliferation along with varying amount of inflammatory infiltrate. A number of terms have been applied to the lesion, namely, inflammatory pseudotumor, fibrous xanthoma, plasma cell granuloma, pseudosarcoma, lymphoid hamartoma, myxoid hamartoma, inflammatory myofibrohistiocytic proliferation, benign myofibroblatoma, and most recently, inflammatory myofibroblastic tumor.
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