Free radicals are implicated in various chronic diseases. There has always been a search for new antioxidants. In this paper we have investigated Tamra bhasma, a metallic ayurvedic preparation. It is a time-tested medicine in Ayurveda and is in clinical use for various ailments specifically the free radical mediated diseases. Our results show that Tamra bhasma inhibits lipid peroxidation (LPO), prevents the rate of aerial oxidation of reduced glutathione (GSH) content and induces the activity of superoxide dismutase (SOD) in rat liver homogenate in the bi-phasic manner. The drug was orally given for 7, 15 and 30 days in different doses. Best protective response was found at the dose of 0.5mg/100g body weight in albino rats, although it showed some histopathological changes at the dose of 20mg/100g body weight. The results suggest that this Ayurvedic preparation is not merely a source of copper metal, but it is a strong anti-oxidant with no detectable adverse effect in lower doses of therapeutic range.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3453883 | PMC |
| http://dx.doi.org/10.1007/BF02867385 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Product development and characterization of the Ayurvedic herbo-mineral-metallic compound- Hridayarnava Rasa.
J Ayurveda Integr Med
May 2024
Dr. Sarvepalli Radhakrishnan Rajasthan Ayurved University, Jodhpur, Rajasthan - 342037, India.
Article Synopsis
- Herbo-mineral-metallic formulations, like Hridayarnava Rasa (HR), are used in Ayurveda for treating cardiac diseases, with a focus on quality, safety, and efficacy in their preparation.
- The study aimed to prepare HR according to traditional procedures and analyze its properties using advanced techniques like XRD and SEM.
- Results showed the presence of specific metals, nanocrystallite particle structures, and detailed characteristics such as 18 peaks in FTIR analysis, highlighting its potential therapeutic applications.
Preliminary data on cytotoxicity and functional group assessment of a herb-mineral combination against colorectal carcinoma cell line.
J Complement Integr Med
March 2024
Department of Rasa Shastra and Bhaishajya Kalpana, Banaras Hindu University, Varanasi, India.
Objectives: The invasive screening methods and the late stage diagnosis of colorectal carcinoma (CRC) are contributing for the devastative prognosis. The gradual shift of the disease pattern among younger generations requires the implementation of phytochemicals and traditional medicines. (AR) is a herb-mineral combination of /incinerated copper ashes and /mercury sulphide levigated with leaf juice, root decoction and the decoction of three myrobalans (, , decoction)/ decoction.
View Article and Find Full Text PDFExploring the efficacy of panchavalkal extract and Zinc-Copper Bhasma in promoting wound healing in incision and excision wound models in the rat.
J Ethnopharmacol
February 2024
Saraswathi Vidya Bhavan's College of Pharmacy, Dombivli, India. Electronic address:
Ethnopharmacological Relevance: Modified Panchavalkal (MPVKL) and herbomineral Preparations as per the Ayurvedic texts possess various medicinal properties. Although some of its pharmacological benefits have been documented, scientific validation of combined wound-healing properties has not been done.
Aim: To investigate the effects of the herbomineral combinations of MPVKL extract on wound healing efficacy through the utilization of incision and excision rodent models.
Ayurvedic metal nanoparticles could be novel antiviral agents against SARS-CoV-2.
Int Nano Lett
January 2021
Centre for Healthcare Science and Technology, Indian Institute of Engineering Science Technology, Shibpur, Howrah, 711103 West Bengal India.
Purpose Of Review: The pandemic COVID-19 has affected more than seventy million people globally. The whole world is eagerly waiting for an effective antiviral therapy to combat COVID-19, but it is yet to get. The emergence of COVID-19 makes imperative the need for safe and potent antiviral drugs.
View Article and Find Full Text PDFStudy on physical properties of Ayurvedic nanocrystalline Tamra Bhasma by employing modern scientific tools.
J Ayurveda Integr Med
December 2017
Department of Physics, Indian Institute of Technology (IIT) Patna, Bihta, 801103, India.
Background: Tamra Bhasma is derived from metallic copper that is recommended for different ailments of liver and spleen, dropsy, abdominal pain, heart disease, colitis, tumors, anemia, loss of appetite, tuberculosis, as well as eye problems.
Objectives: The knowledge of crystallite size and active ingredients in Bhasma materials is limited restricting its use as nanomedicine in the modern era. Also, the 2015 Nobel prize in medicine has motivated many researchers towards traditional medicines.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!