Objective: The purpose of this study is to evaluate the role of ultrasonography (US) in the management of thyroid nodules when the cytology is benign tumor on fine needle aspiration biopsy (FNAB).
Methods: Between 2006 and 2011, we investigated 13,972 patients who had solitary thyroid nodule with cytological findings of benign. Surgery was performed according to our criteria for surgical indication. Of these patients, 1877 (13%) patients who underwent surgery were enrolled in this study. We compared the results of clinical findings including US classification and final histopathological diagnosis.
Results: One hundred seven (6%) after surgery were diagnosed as malignancy pathologically. Large nodule or high serum thyroglobulin level were not associated with an increased risk of malignancy. Ultrasonographic evaluation as malignancy was directly linked to pathological diagnosis as thyroid carcinoma (p<0.001).
Conclusion: US may help to play a role in deciding whether surgical treatment is necessary for cytologically benign thyroid nodules.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.anl.2012.09.007 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Somatic copy number deletion of chromosome 22q in papillary thyroid carcinoma.
Eur Thyroid J
January 2025
S Chanock, Division of Cancer Epidemiology and Genetics, Laboratory of Genetic Susceptibility, National Cancer Institute, Bethesda, United States.
Deletion of the long q arm of chromosome 22 (22qDEL) is the most frequently identified recurrent somatic copy number alteration (SCNA) observed in papillary thyroid carcinoma (PTC). Since its role in PTC is not fully understood, we conducted a pooled analysis of genomic characteristics and clinical correlates in 1094 primary tumors from four published PTC genomic studies. The majority of PTC with 22qDEL exhibited arm-level loss of heterozygosity (86%); nearly all PTC with 22qDEL had losses in 22q12 and 13, which together constitute 70% of the q arm.
View Article and Find Full Text PDFThe Prevalence of Local Symptoms in Benign Thyroid Disease: A Systematic Review with Meta-analysis.
Laryngoscope
December 2024
Faculty of Medicine, Nursing, and Health Sciences, Monash University, Clayton, Victoria, Australia.
Objective: This systematic review seeks to evaluate the prevalence of local symptoms in patients with benign thyroid disease as described in the literature.
Data Sources: A literature search was conducted across PubMed, Embase, Medline, and Cochrane databases.
Review Methods: Crude symptom prevalence was obtained by addition of data across studies that reported local symptoms, and adjusted symptom frequency was calculated using a random effects model.
Arrival-Time Parametric Imaging in Contrast-Enhanced Ultrasound for Thyroid Nodule Differentiation.
Med Sci Monit
December 2024
Department of Ultrasound Diagnosis, General Hospital of Northern Theater Command, Shenyang, Liaoning, China.
BACKGROUND Solitary thyroid nodules present a challenge in differentiating between benign and malignant conditions using ultrasound (US). Arrival time parameter imaging (At-PI) following contrast-enhanced ultrasound (CEUS) can effectively visualize the vascular architectural patterns of the nodules, providing valuable diagnostic information. This study aimed to explore the application value of At-PI in differentiating thyroid nodules, specifically focusing on a sample of 127 cases.
View Article and Find Full Text PDFRadiofrequency Ablation for Solitary Autonomously Functioning Thyroid Nodules: Multicenter Study from Latin America.
Thyroid
December 2024
Oncology Center, Oswaldo Cruz German Hospital, São Paulo, Brazil.
Autonomously functioning thyroid nodules (AFTNs) represent ∼5% of all thyroid nodules and often necessitate definitive treatments such as surgery or radioiodine (I), both of which have inherent risks. Radiofrequency ablation (RFA) has emerged as an effective and safe therapeutic option for managing AFTNs. This study aims to assess the effectiveness and safety of RFA for solitary AFTNs in various countries across Latin America.
View Article and Find Full Text PDFMetastatic papillary thyroid carcinoma in the soft tissue of the breast in a male patient: A case report.
Oncol Lett
February 2025
Department of Radiology, University Hospital Olomouc, Olomouc 77900, Czech Republic.
Papillary thyroid carcinoma (PTC) represents ~80% of all thyroid cancers, most frequently presenting in women in the third and fourth decade of life. The first clinical manifestation of PTC commonly includes a palpable mass in the thyroid area or cervical lymphadenopathy in cases of metastatic disease. Hematogenous distant metastases are a sign of an advanced stage of the tumour.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!