A lack of tools has hampered the search for the potential functions of the abundant noncoding RNA (ncRNA) portion of the genome. Wan et al. (2012) report a new sequencing-based method for determining ncRNA secondary structure termed PARTE, promising to accelerate ncRNA studies.
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http://dx.doi.org/10.1016/j.molcel.2012.10.004 | DOI Listing |
FASEB J
January 2025
Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
With the emergence of high-quality sequencing technologies, further research on transcriptomes has become possible. Circular RNA (circRNA), a novel type of endogenous RNA molecule with a covalently closed circular structure through "back-splicing," is reported to be widely present in eukaryotic cells and participates mainly in regulating gene and protein expression in various ways. It is becoming a research hotspot in the non-coding RNA field.
View Article and Find Full Text PDFJ Endocrinol Invest
January 2025
Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Histol Histopathol
February 2025
Department of Intensive Care Unit, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
The authors regret the paper was published with an error in Figure 3B sh-NC+HI group. The H&E image in 3B sh-NC+HI group should be corrected as follows. This correction has no influence on the conclusion and the main text of the article.
View Article and Find Full Text PDFHLA
February 2025
Temple University Hospital Philadelphia, Philadelphia, Pennsylvania, USA.
The full-length sequence of HLA-DQB1*06:304N covers the 5'-untranslated region (UTR), all introns and exons, and the 3' UTR.
View Article and Find Full Text PDFDis Model Mech
January 2025
Department of Microbiology, Trinity College, Dublin D02 VF25, Ireland.
Gestational trophoblastic disease (GTD) describes a group of rare benign and cancerous lesions originating from the trophoblast cells of the placenta. These neoplasms are unconventional entities, being one of the few instances in which cancer develops from the cells of another organism, the foetus. Although this condition was first described over 100 years ago, the specific genetic and non-genetic drivers of this disease remain unknown to this day.
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