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A Case of Purpuric Papulopustular Eruption on the Extremities Developed During Erlotinib and Ramucirumab Combination Treatment, Resulting in Complete Regression Without Oral Prednisone or Discontinuing Chemotherapy.
Cureus
December 2024
Department of Dermatology, International University of Health and Welfare Narita Hospital, Narita, JPN.
A 53-year-old woman undergoing combination therapy with epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR) inhibitors for advanced lung cancer with brain metastases developed pustules and punctate purpura on both lower extremities. Histopathological examination revealed neutrophilic infiltration around the hair follicles and erythrocyte extravasation in the perivascular regions near the hair roots, leading to a diagnosis of purpuric papulopustular eruptions. The rash improved with oral doxycycline (100 mg/day) and topical corticosteroids.
View Article and Find Full Text PDFScurvy masquerading as IgA vasculitis.
Pediatr Rheumatol Online J
May 2024
Red Cross Children's Hospital, University of Cape Town, Cape Town, South Africa.
Background: Vitamin C deficiency, or scurvy, is rare but poses risks for children with poor diets, limited resources, or malabsorption issues. It may also be common in children with restrictive or selective dietary habits in children with global developmental delay, autism spectrum disorder, and physical disabilities. Symptoms include fatigue, irritability, joint and muscle pain, joint swellings, edema, swollen gums, easy bruising, and delayed wound healing.
View Article and Find Full Text PDFDemodicosis Associated with Wearing a Face Mask: A Case Report.
Case Rep Dermatol
February 2022
School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Wattana, Bangkok, Thailand.
mites are common ectoparasites of human pilosebaceous units that do not cause any skin symptoms. However, when there is an abnormal increase in mite density, it can cause multiple skin disorders which are grouped under the term demodicosis. During the COVID-19 outbreak, public health authorities worldwide recommend people to wear face masks when in public places to reduce respiratory transmission.
View Article and Find Full Text PDFClinical and trichoscopic features in 18 cases of Folliculotropic Mycosis Fungoides with scalp involvement.
Sci Rep
May 2021
Division of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Folliculotropic Mycosis Fungoides (FMF) is a rare variant of Mycosis Fungoides involving the scalp leading to alopecia. The clinical and trichoscopic features in 18 patients were analyzed and compared with the reports in the literature. Gender, age, disease stage, site of onset were taken into consideration.
View Article and Find Full Text PDFBackground:: Pigmented purpuric dermatosis is a chronic skin disorder of unknown aetiology characterised by symmetrical petechial and pigmented macules, often confined to the lower limbs. The aetiology of pigmented purpuric dermatosis is unknown. Dermatoscopy is a non-invasive diagnostic technique that allows the visualisation of morphological features invisible to the naked eye; it combines a method that renders the corneal layer of the skin translucent with an optical system that magnifies the image projected onto the retina.
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