L-asparaginase induced fatal cortical venous thrombosis in acute lymphoblastic leukemia.

Indian J Hematol Blood Transfus

Department of Medical Oncology, Cancer Institute, 18 Sardar Patel Road, Guindy, Chennai, 600 036 India.

Published: March 2010

L-asparaginase has become an integral part in the treatment of acute lymphoblastic leukemia. The major worry of using L-asparaginase is thromboembolism. The case presented here is a 21-year-old lady who developed fatal cortical venous thrombosis during induction phase of treatment for ALL. Early recognition is very important to treat this potentially catastrophic yet treatable complication.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3452943PMC
http://dx.doi.org/10.1007/s12288-010-0005-7DOI Listing

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