Umbilical cord blood is an established source of stem cells useful for hematopoetic reconstitution. The first clinical transplantation in France by Eliane Gluckman in 1988 using HLA matched umbilical cord blood from a sibling on a 6-year-old boy with Fanconi's anemia is an example of a successful transplantation. So far, more than 8,000 patients worldwide have been treated for malignant and inherent blood disorders [1, 2]. Our cord blood repository (CBR) was established as the part of the Life Sciences initiative, almost 7 years ago. The cord blood program consisted of developing a good network of obstetricians and social workers, develop manpower in various aspects of the banking activity, develop methods of process and analysis and above all, increase the level of awareness among the medical, paramedical fraternity and the general public on the cord blood program. The present paper gives a detailed account of our experience as we set up the repository.
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http://dx.doi.org/10.1007/s12288-009-0023-5 | DOI Listing |
Biomed Res Int
January 2025
College of Agriculture and Veterinary Medicine, Jimma University, Jimma, Ethiopia.
Bovine viral diarrhea virus (BVDV) is an important pathogen affecting dairy cattle all over the world by causing significant economic losses due to reproductive and respiratory problems, immunosuppressive effects, increased risk of morbidity, and calf mortality. A cross-sectional study was conducted from February 2021 to August 2021 to determine the seroprevalence of bovine viral diarrhea (BVD) and identify risk factors associated with its occurrence in and around Nekemte Town of Ethiopia. Blood samples were collected from 305 dairy cattle of 41 herds by using cluster-sampling method.
View Article and Find Full Text PDFCase Rep Neurol Med
January 2025
Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Determining the differential diagnosis of small scalp cysts identified on a fetus is difficult. In particular, many physicians have difficulty differentiating small meningoceles from small scalp cysts during the prenatal period. Volume contrast imaging increases contrast between tissues, thereby allowing an enhanced view of target structures.
View Article and Find Full Text PDFRSC Med Chem
January 2025
School of Chemistry, University of Glasgow, University Avenue Glasgow G12 8QQ UK
The sphingosine-1-phosphate-5 (S1P) receptor is one of the five membrane G protein-coupled receptors that are activated by the lysophospholipid, sphingosine-1-phosphate, resulting in regulation of many cellular processes. S1P receptors are located on oligodendrocytes and are proposed to influence oligodendrocyte physiology. Understanding S1P modulation during processes such as remyelination could have potential applications for demyelinating CNS disorders such as multiple sclerosis (MS).
View Article and Find Full Text PDFNarra J
December 2024
Center for Preventive Medical Sciences, Chiba University, Chiba, Japan.
A worldwide issue, vitamin D deficiency affects pregnant mothers and babies everywhere, including Indonesia. It involves the adaptive immune system by controlling the production of pro-and anti-inflammatory cytokines and the balance between humoral (Th2) and cell-mediated (Th1) immunity. The aim of this study was to investigate the relationship between vitamin D and the cytokines IL-6 and IL-10 in infants.
View Article and Find Full Text PDFRegen Med
January 2025
Biorepository, University of Arizona, Tucson, AZ, USA.
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