Cystic echinococcosis is regarded as endemic in sub-Saharan Africa; however, for most countries only scarce data, if any, exist. For most of the continent, information about burden of disease is not available; neither are data for the animal hosts involved in the lifecycle of the parasite, thus making introduction of preventive measures difficult. Available evidence suggests that several species or strains within the Echinococcus granulosus complex are prevalent in sub-Saharan Africa and that these strains might be associated with varying virulence and host preference. Treatment strategies (chemotherapy, percutaneous radiological techniques, but mainly surgery) predominantly target active disease. Prevention strategies encompass anthelmintic treatment of dogs, slaughter hygiene, surveillance, and health-educational measures. Existing data are suggestive of unusual clinical presentations of cystic echinococcosis in some parts of the continent, for which the causes are speculative.
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http://dx.doi.org/10.1016/S1473-3099(12)70155-X | DOI Listing |
Oxf Med Case Reports
January 2025
Neurosurgery Department, Al-Ahli Hospital, Hebron, 00970, Palestine.
Echinococcus larval stage or a hydatid cyst, a parasitic disease that passes from animals to humans. Echinococcus granulosus and, less commonly, Echinococcus multilocularis species cause the disease. Intracranial echinococcosis is rare, with an incidence of approximately 1%-2%.
View Article and Find Full Text PDFFront Genet
January 2025
Key Laboratory of Intelligent Computing and Signal Processing, School of Artificial Intelligence, Anhui University, Hefei, China.
Echinococcosis is a zoonotic parasitic disease caused by the larvae of echinococcus tapeworms infesting the human body. Drug combination therapy is highly valued for the treatment of echinococcosis because of its potential to overcome resistance and enhance the response to existing drugs. Traditional methods of identifying drug combinations via biological experimentation is costly and time-consuming.
View Article and Find Full Text PDFBMC Infect Dis
January 2025
Department of Critical Care Medicine, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi, 830054, China.
Background: Echinococcosis is a zoonotic parasitic disease prevalent in pastoral areas, mainly involving the liver and lungs, and rarely affecting the brain and heart. This article describes the diagnosis and treatment of 14 patients with cardiac encapsulated cysts, with the aim of providing insights into the clinical presentation, diagnostic challenges, therapeutic strategies, and outcomes associated with cardiac encapsulated cysts.
Methods: This retrospective case series included 13 patients with cardiac and/or cerebral encapsulated cysts.
Indian J Pediatr
January 2025
Department of Radiology, Istanbul Medipol University, Istanbul, Turkey.
Zhonghua Yu Fang Yi Xue Za Zhi
January 2025
Department of Basic Medicine, College of Medicine, Qinghai University, Xining810016, China.
Exploring the variability of the intestinal flora of patients with hepatic blastocysticercosis and searching for members of the intestinal microflora that may play a role in the disease process by means of macro-genome sequencing technology. A case-control study was used to include fecal samples from patients with hepatic vesicular schistosomiasis admitted to Qinghai Provincial People's Hospital between October 2023 and January 2024 and individuals attending health checkups. The experimental group (AE group) consisted of 10 patients with liver vesicular schistosomiasis and the control group (NC group) consisted of 9 individuals attending health checkups.
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